A Bone Tumor-like Chest Wall Mass Lesion with Pathological Rib Fractures Observed 13 years After Lung Stereotactic Body Radiotherapy: A Case Report
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Although stereotactic body radiotherapy (SBRT) is a curative treatment option for stage I non-small cell lung cancer (NSCLC), limited data are available regarding chest wall (CW) toxicities during an extended follow-up of over 10 years. We report an unusual case of a bone tumor-like CW mass lesion with pathological rib fractures observed 13 years after SBRT for peripheral lung cancer. Despite the initial suspicion of radiation-induced sarcoma, a subsequent incisional biopsy revealed no evidence of malignancy, and a definitive diagnosis of osteonecrosis was made. Thus, long-term observation of over 10 years is required to identify late chronic complications following SBRT.
Matsuda M, Ichikawa J, Komiyama T, Onohara K, Saito M, Nemoto H Thorac Cancer. 2024; 15(26):1912-1916.
PMID: 39113470 PMC: 11462948. DOI: 10.1111/1759-7714.15419.