Infiltrating Lobular Carcinoma of LUMB HER2+ Subtype with Rhabdoid Feature Coexisting with Synchronous Malignant Transformation of Phyllodes Tumor: An Exceedingly Rare Clinicopathological Characteristic in Vietnam

Overview

Journal Rare Tumors

Publisher Sage Publications

Specialty Oncology

Date 2024 Aug 7

PMID 39108547

Authors

Tu Anh Do

Nhung Thi Mai

Duong Ngoc Nguyen

Khoa Hong Pham

Duc Thanh Le

Hung Van Pham

Chu Van Nguyen

Affiliations

Soon will be listed here.

Abstract

The transformation of a benign phyllodes tumor (PT) into a malignant PT and/or carcinoma is extremely uncommon. We present a case of a 66-year-old female with a huge mass on the left breast which was successfully removed by surgical resection. The pathological diagnosis was infiltrating lobular carcinoma with pure rhabdoid features and the malignant transformation of a benign phyllodes tumor. The first time this rare case was reported, it is demonstrated a special phenomenon through the synchronous transformation of PT grades and the carcinomatous transformation of PT.

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