Synthesis of Highly Unsaturated Phosphatidylcholines in the Development of Sperm Motility: a Role for Epididymal Glycerol-3-phosphorylcholine

Overview

Journal Mol Cell Biochem

Publisher Springer

Specialty Biochemistry

Date 1985 Nov 1

PMID 3908909

Citations 5

Authors

J P Infante

V A Huszagh

Affiliations

Soon will be listed here.

Abstract

Interpretation of the experimental literature on epididymal glycerophosphorylcholine metabolism according to a recently proposed de novo pathway for the synthesis of acyl-specific phosphatidylcholine suggests that epididymal glycerophosphorylcholine is an intermediate of this proposed pathway. This glycerophosphodiester is postulated to be utilized by spermatozoa to synthesize docosahexaenoic phosphatidylcholine, proposed to be required for the development of sperm motility. A defect in glycerophosphorylcholine synthesis might be responsible for some forms of asthenozoospermia.

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