» Articles » PMID: 39045260

Evaluating the Association of Female Obesity with the Risk of Live Birth Following IVF: Implications for Clinical Practice

Overview
Journal Pract Midwife
Date 2024 Jul 24
PMID 39045260
Authors
Affiliations
Soon will be listed here.
Abstract

Obesity is a well-established risk factor for infertility. Consequentially, women living with obesity may require fertility treatment to support them to conceive. Due to evidence suggesting obesity is also linked with poorer outcomes following in vitro fertilisation (IVF), local commissioning guidelines on assisted conception recommend a BMI of <30kg/m before IVF can commence. However, it is currently unclear if these guidelines are evidence based. This commentary aims to critically appraise a recent systematic review by Sermondade et al, 2019 and expand upon the implications of the findings for clinical practice.

References
1.
Zhou H, Zhang D, Luo Z, Yang A, Cui N, Hao G . Association between Body Mass Index and Reproductive Outcome in Women with Polycystic Ovary Syndrome Receiving IVF/ICSI-ET. Biomed Res Int. 2020; 2020:6434080. PMC: 7463361. DOI: 10.1155/2020/6434080. View

2.
Gorry A, White D, Franks S . Infertility in polycystic ovary syndrome: focus on low-dose gonadotropin treatment. Endocrine. 2006; 30(1):27-33. DOI: 10.1385/ENDO:30:1:27. View

3.
Tremellen K, Wilkinson D, Savulescu J . Should obese women's access to assisted fertility treatment be limited? A scientific and ethical analysis. Aust N Z J Obstet Gynaecol. 2017; 57(5):569-574. DOI: 10.1111/ajo.12600. View

4.
Kumar R, Rizvi M, Saraswat S . Obesity and Stress: A Contingent Paralysis. Int J Prev Med. 2022; 13:95. PMC: 9362746. DOI: 10.4103/ijpvm.IJPVM_427_20. View

5.
Azziz R, Carmina E, Chen Z, Dunaif A, Laven J, Legro R . Polycystic ovary syndrome. Nat Rev Dis Primers. 2016; 2:16057. DOI: 10.1038/nrdp.2016.57. View