Vitamin D Binding Protein in Psychiatric and Neurological Disorders: Implications for Diagnosis and Treatment

Overview

Journal Genes Dis

Date 2024 Jul 10

PMID 38983447

Authors

Ling Li

Bing Han

Yan Kong

Gaojia Zhang

Zhijun Zhang

Affiliations

Soon will be listed here.

Abstract

Vitamin D binding protein (VDBP) serves as a key transporter protein responsible for binding and delivering vitamin D and its metabolites to target organs. VDBP plays a crucial part in the inflammatory reaction following tissue damage and is engaged in actin degradation. Recent research has shed light on its potential role in various diseases, leading to a growing interest in understanding the implications of VDBP in psychiatric and neurological disorders. The purpose of this review was to provide a summary of the existing understanding regarding the involvement of VDBP in neurological and psychiatric disorders. By examining the intricate interplay between VDBP and these disorders, this review contributes to a deeper understanding of underlying mechanisms and potential therapeutic avenues. Insights gained from the study of VDBP could pave the way for novel strategies in the diagnosis, prognosis, and treatment of psychiatric and neurological disorders.

Citing Articles

Causal Relationships Between Epilepsy, Anti-Epileptic Drugs, and Serum Vitamin D and Vitamin D Binding Protein: A Bidirectional and Drug Target Mendelian Randomization Study.

Cheng Z, Zuo J, Peng X, Zhang H, Su W, Luan G CNS Neurosci Ther. 2024; 30(12):e70183.

PMID: 39703113 PMC: 11659638. DOI: 10.1111/cns.70183.

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