» Articles » PMID: 38949639

Kids' Noses Resist COVID-19

Overview
Journal J Exp Med
Date 2024 Jul 1
PMID 38949639
Authors
Affiliations
Soon will be listed here.
Abstract

Children resist COVID-19, and previous studies reported increased innate immunity in their upper airways. A new paper by Watkins et al. (https://doi.org/10.1084/jem.20230911) shows that the nasal mucosa of children is characterized by often asymptomatic viral and/or bacterial infections that dynamically regulate distinct innate immune programs.

References
1.
Cheemarla N, Watkins T, Mihaylova V, Wang B, Zhao D, Wang G . Dynamic innate immune response determines susceptibility to SARS-CoV-2 infection and early replication kinetics. J Exp Med. 2021; 218(8). PMC: 8210587. DOI: 10.1084/jem.20210583. View

2.
Akusjarvi S, Zanoni I . Yin and yang of interferons: lessons from the coronavirus disease 2019 (COVID-19) pandemic. Curr Opin Immunol. 2024; 87:102423. PMC: 11162909. DOI: 10.1016/j.coi.2024.102423. View