» Articles » PMID: 38892878

Arrhythmias in Cardiac Sarcoidosis: Management and Prognostic Implications

Overview
Journal J Clin Med
Specialty General Medicine
Date 2024 Jun 19
PMID 38892878
Authors
Affiliations
Soon will be listed here.
Abstract

Cardiac sarcoidosis (CS) is characterized by various arrhythmic manifestations ranging from catastrophic sudden cardiac death secondary to ventricular arrhythmia, severe conduction disease, sinus node dysfunction, and atrial fibrillation. The management of CS is complex and includes not only addressing the arrhythmia but also controlling the myocardial inflammation resultant from the autoimmune reaction. Arrhythmic manifestations of CS carry significant prognostic implications and invariably affect long-term survival in these patients. In this review, we focus on management of arrhythmic manifestation of cardiac sarcoidosis as well as risk stratification for sudden cardiac death in these patients.

Citing Articles

Outcomes of catheter ablation in cardiac sarcoidosis patients with ventricular tachycardia: a propensity score-matched retrospective analysis.

Al Taii H, Saxena R, Morcos R, Al-Shammari A, Farhat K, Al Sakini A J Interv Card Electrophysiol. 2025; .

PMID: 39786700 DOI: 10.1007/s10840-025-01986-0.


Contemporary Diagnostics of Cardiac Sarcoidosis: The Importance of Multimodality Imaging.

Stjepanovic M, Markovic F, Milivojevic I, Popevic S, Dimic-Janjic S, Popadic V Diagnostics (Basel). 2024; 14(17).

PMID: 39272650 PMC: 11394254. DOI: 10.3390/diagnostics14171865.

References
1.
Haanschoten D, Adiyaman A, t Hart N, Jager P, Elvan A . Value of 3D mapping-guided endomyocardial biopsy in cardiac sarcoidosis: Case series and narrative review on the value of electro-anatomic mapping-guided endomyocardial biopsies. Eur J Clin Invest. 2021; 51(4):e13497. DOI: 10.1111/eci.13497. View

2.
Slaughter M, Rogers J, Milano C, Russell S, Conte J, Feldman D . Advanced heart failure treated with continuous-flow left ventricular assist device. N Engl J Med. 2009; 361(23):2241-51. DOI: 10.1056/NEJMoa0909938. View

3.
Ezzeddine F, Kapa S, Rosenbaum A, Blauwet L, Deshmukh A, AbouEzzeddine O . Electrogram-guided endomyocardial biopsy yield in patients with suspected cardiac sarcoidosis and relation to outcomes. J Cardiovasc Electrophysiol. 2021; 32(9):2486-2495. DOI: 10.1111/jce.15191. View

4.
Nakajo M, Hirahara D, Jinguji M, Ojima S, Hirahara M, Tani A . Machine learning approach using F-FDG-PET-radiomic features and the visibility of right ventricle F-FDG uptake for predicting clinical events in patients with cardiac sarcoidosis. Jpn J Radiol. 2024; 42(7):744-752. PMC: 11217075. DOI: 10.1007/s11604-024-01546-y. View

5.
Nordenswan H, Poyhonen P, Lehtonen J, Ekstrom K, Uusitalo V, Niemela M . Incidence of Sudden Cardiac Death and Life-Threatening Arrhythmias in Clinically Manifest Cardiac Sarcoidosis With and Without Current Indications for an Implantable Cardioverter Defibrillator. Circulation. 2022; 146(13):964-975. PMC: 9508990. DOI: 10.1161/CIRCULATIONAHA.121.058120. View