Impact of Lactic Acid Bacteria Fermentation Based on Biotransformation of Phenolic Compounds and Antioxidant Capacity of Mushrooms

Overview

Journal Foods

Specialty Biotechnology

Date 2024 Jun 19

PMID 38890845

Authors

Eda Nur Ayar-Sumer

Yannick Verheust

Beraat Ozcelik

Katleen Raes

Affiliations

Soon will be listed here.

Abstract

Mushrooms contain phenolic compounds that possess health-promoting properties, including antioxidant effects. However, the low solubility and form of phenolic compounds affect their bioactivity and bioaccessibility. To overcome this limitation, our study investigates the fermentation of mushrooms to increase their free phenolic content and enhance their bioactivity. Our research focused on the impact of fermentation on both free and bound phenolic fractions (FPs and BPs, respectively) in and , which were successively fermented with for 72 h. We examined the total phenolic content (TPC), phenolic profile, and antioxidant activity of both FPs and BPs. Our results showed that the TPC of BPs was higher than that of FPs in both mushrooms, with strong antioxidant capabilities. Fermentation significantly increased the TPC of FPs in both mushrooms, particularly after 24 h of fermentation. The TPC of BPs in mushrooms decreased during fermentation, indicating their release from the matrix. Additionally, we identified 30 bioactive compounds using UPLC-Q-TOF-MS/MS. Our study demonstrates for the first time that lactic acid bacteria fermentation of mushrooms with high phenolic content leads to the liberation of bound phenolics, enhancing their bioactivity and bioaccessibility.

References

Degrain A, Manhivi V, Remize F, Garcia C, Sivakumar D . Effect of Lactic Acid Fermentation on Color, Phenolic Compounds and Antioxidant Activity in African Nightshade. Microorganisms. 2020; 8(9). PMC: 7564239. DOI: 10.3390/microorganisms8091324. View

Lubbers R, Dilokpimol A, Visser J, Makela M, Hilden K, de Vries R . A comparison between the homocyclic aromatic metabolic pathways from plant-derived compounds by bacteria and fungi. Biotechnol Adv. 2019; 37(7):107396. DOI: 10.1016/j.biotechadv.2019.05.002. View

Gonzales G, Raes K, Coelus S, Struijs K, Smagghe G, Van Camp J . Ultra(high)-pressure liquid chromatography-electrospray ionization-time-of-flight-ion mobility-high definition mass spectrometry for the rapid identification and structural characterization of flavonoid glycosides from cauliflower waste. J Chromatogr A. 2013; 1323:39-48. DOI: 10.1016/j.chroma.2013.10.077. View

Tu J, Brennan M, Wu G, Bai W, Cheng P, Tian B . Delivery of Phenolic Compounds, Peptides and β-Glucan to the Gastrointestinal Tract by Incorporating Dietary Fibre-Rich Mushrooms into Sorghum Biscuits. Foods. 2021; 10(8). PMC: 8391148. DOI: 10.3390/foods10081812. View

Yao F, Gao H, Yin C, Shi D, Fan X . Effect of Different Cooking Methods on the Bioactive Components, Color, Texture, Microstructure, and Volatiles of Shiitake Mushrooms. Foods. 2023; 12(13). PMC: 10340526. DOI: 10.3390/foods12132573. View

Yang J, Sun Y, Gao T, Wu Y, Sun H, Zhu Q . Fermentation and Storage Characteristics of "Fuji" Apple Juice Using and : Microbial Growth, Metabolism of Bioactives and Bioactivities. Front Nutr. 2022; 9:833906. PMC: 8864132. DOI: 10.3389/fnut.2022.833906. View

Antunes F, Marcal S, Taofiq O, Morais A, Freitas A, Ferreira I . Valorization of Mushroom By-Products as a Source of Value-Added Compounds and Potential Applications. Molecules. 2020; 25(11). PMC: 7321189. DOI: 10.3390/molecules25112672. View

Yang J, Gao T, Ge F, Sun H, Cui Z, Wei Z . Sauces Fermented With Lactic Acid Bacteria: Fermentation Properties, Flavor Profile, and Evaluation of Antioxidant Capacity . Front Nutr. 2022; 8:810460. PMC: 8805458. DOI: 10.3389/fnut.2021.810460. View

Yeo J, Tsao R, Sun Y, Shahidi F . Liberation of insoluble-bound phenolics from lentil hull matrices as affected by Rhizopus oryzae fermentation: Alteration in phenolic profiles and their inhibitory capacities against low-density lipoprotein (LDL) and DNA oxidation. Food Chem. 2021; 363:130275. DOI: 10.1016/j.foodchem.2021.130275. View

10.

Li Z, Teng J, Lyu Y, Hu X, Zhao Y, Wang M . Enhanced Antioxidant Activity for Apple Juice Fermented with ATCC14917. Molecules. 2018; 24(1). PMC: 6337214. DOI: 10.3390/molecules24010051. View

11.

Yang J, Sun Y, Chen J, Cheng Y, Zhang H, Gao T . Fermentation of ginkgo biloba kernel juice using Y2 from the ginkgo peel: Fermentation characteristics and evolution of phenolic profiles, antioxidant activities , and volatile flavor compounds. Front Nutr. 2022; 9:1025080. PMC: 9649921. DOI: 10.3389/fnut.2022.1025080. View

12.

Adebo O, Medina-Meza I . Impact of Fermentation on the Phenolic Compounds and Antioxidant Activity of Whole Cereal Grains: A Mini Review. Molecules. 2020; 25(4). PMC: 7070691. DOI: 10.3390/molecules25040927. View

13.

Carvalho D, Guido L . A review on the fate of phenolic compounds during malting and brewing: Technological strategies and beer styles. Food Chem. 2021; 372:131093. DOI: 10.1016/j.foodchem.2021.131093. View

14.

Wen D, Li C, Di H, Liao Y, Liu H . A universal HPLC method for the determination of phenolic acids in compound herbal medicines. J Agric Food Chem. 2005; 53(17):6624-9. DOI: 10.1021/jf0511291. View

15.

Wang Y, Wu J, Lv M, Shao Z, Hungwe M, Wang J . Metabolism Characteristics of Lactic Acid Bacteria and the Expanding Applications in Food Industry. Front Bioeng Biotechnol. 2021; 9:612285. PMC: 8149962. DOI: 10.3389/fbioe.2021.612285. View

16.

Pehlivan Karakas F, Ucar Turker A, Bozat B . Phenolic Content, Antibacterial and Antioxidant Potential of Several Edible Agaricomycetes Mushrooms Sold in Public Bazaar in Bolu, Turkey. Int J Med Mushrooms. 2023; 25(1):45-56. DOI: 10.1615/IntJMedMushrooms.2022046526. View

17.

Zhang D, Ye Y, Tan B . Comparative study of solid-state fermentation with different microbial strains on the bioactive compounds and microstructure of brown rice. Food Chem. 2022; 397:133735. DOI: 10.1016/j.foodchem.2022.133735. View

18.

Leong Y, Ma T, Chang J, Yang F . Recent advances and future directions on the valorization of spent mushroom substrate (SMS): A review. Bioresour Technol. 2021; 344(Pt A):126157. DOI: 10.1016/j.biortech.2021.126157. View

19.

Jablonska-Rys E, Skrzypczak K, Slawinska A, Radzki W, Gustaw W . Lactic Acid Fermentation of Edible Mushrooms: Tradition, Technology, Current State of Research: A Review. Compr Rev Food Sci Food Saf. 2020; 18(3):655-669. DOI: 10.1111/1541-4337.12425. View

20.

Gonzales G, Smagghe G, Raes K, Van Camp J . Combined alkaline hydrolysis and ultrasound-assisted extraction for the release of nonextractable phenolics from cauliflower (Brassica oleracea var. botrytis) waste. J Agric Food Chem. 2014; 62(15):3371-6. DOI: 10.1021/jf500835q. View