A Rare Cause of Bronchial Obstruction: Endobronchial Hamartoma Case Report

Overview

Journal Radiol Case Rep

Publisher Elsevier

Specialty Radiology

Date 2024 Jun 14

PMID 38872744

Authors

Zineb Bouanani

Asmae Rais

Fatima Zahra Benbrahim

Amal Akammar

Nizar El Bouardi

Meryem Haloua

Youssef My Alaoui Lamrani

Meryem Boubbou

Mounia Serraj

Bouchra Amara

Marouane Lakranbi

Yassine Ouadnouni

Mohammed Smahi

Mustapha Maaroufi

Badreddine Alami

Affiliations

Soon will be listed here.

Abstract

Most of the pulmonary endobronchial lesions are malignant in origin. In rare instances, benign lesions such as endobronchial hamartoma may be the cause of the endobronchial tree obstruction. We present the case of a 57-year-old male patient from North Africa who presents with a history of a 5-month cough. Imaging, particulary CT scan, showed a mass on the right intermediate bronchus whose radiological characteristics are consistent with hamartoma. A biopsy of the mass obtained via bronchoscopy revealed chronic inflammation with no evidence for malignancy. The patient was treated surgically, and anatomopathology confirmed the diagnosis of hamartoma.

References

Rai S, Patil A, Saxena P, Kaur A . Laser resection of endobronchial hamartoma via fiberoptic bronchoscopy. Lung India. 2010; 27(3):170-2. PMC: 2946723. DOI: 10.4103/0970-2113.68329. View

Lien Y, Hsu H, Yin Li W, Wu Y, Hsu W, Wang L . Pulmonary hamartoma. J Chin Med Assoc. 2004; 67(1):21-6. View

Corona F, Okeson G . Endobronchial fibroma: An unusual case of segmental atelectasis. Am Rev Respir Dis. 1974; 110(3):350-3. DOI: 10.1164/arrd.1974.110.3.350. View

Chen S, Zhou H, Tong B, Yu L, Fan S, Xiao Z . Endobronchial hamartoma mimicking malignant lung tumor contralateral endobronchial metastasis: A case report. Medicine (Baltimore). 2017; 96(49):e9085. PMC: 5728943. DOI: 10.1097/MD.0000000000009085. View

Mondello B, Lentini S, Buda C, Monaco F, Familiari D, Sibilio M . Giant endobronchial hamartoma resected by fiberoptic bronchoscopy electrosurgical snaring. J Cardiothorac Surg. 2011; 6:97. PMC: 3170318. DOI: 10.1186/1749-8090-6-97. View

Karabulut N, Bir F, Yuncu G, Kiter G . Endobronchial lipomatous hamartoma: an unusual cause of bronchial obstruction (2007: 7b). Eur Radiol. 2007; 17(10):2687-90. DOI: 10.1007/s00330-006-0534-5. View

Guo W, Zhao Y, Jiang Y, Wang R, Ma Z . Surgical treatment and outcome of pulmonary hamartoma: a retrospective study of 20-year experience. J Exp Clin Cancer Res. 2008; 27:8. PMC: 2438336. DOI: 10.1186/1756-9966-27-8. View

El-Kersh K, Perez R, Gauhar U . A 63-year-old man with a chronic cough and an endobronchial lesion. Diagnosis: Endobronchial hamartoma. Chest. 2014; 145(4):919-922. DOI: 10.1378/chest.13-1965. View

Ahmed S, Arshad A, Mador M . Endobronchial hamartoma; a rare structural cause of chronic cough. Respir Med Case Rep. 2017; 22:224-227. PMC: 5587872. DOI: 10.1016/j.rmcr.2017.08.019. View

10.

Gaerte S, Meyer C, Winer-Muram H, Tarver R, Conces Jr D . Fat-containing lesions of the chest. Radiographics. 2002; 22 Spec No:S61-78. DOI: 10.1148/radiographics.22.suppl_1.g02oc08s61. View

11.

Nussbaumer-Ochsner Y, Rassouli F, Uhlmann F, Thurnheer R . Endobronchial lipoma mimicking bronchial carcinoid tumour. Thorax. 2015; 70(8):809. DOI: 10.1136/thoraxjnl-2015-206923. View

12.

Sharkey R, Mulloy E, ONeill S . Endobronchial hamartoma presenting as massive haemoptysis. Eur Respir J. 1996; 9(10):2179-80. DOI: 10.1183/09031936.96.09102179. View

13.

Stevic R, Milenkovic B . Tracheobronchial tumors. J Thorac Dis. 2017; 8(11):3401-3413. PMC: 5179373. DOI: 10.21037/jtd.2016.11.24. View

14.

Gjevre J, Myers J, Prakash U . Pulmonary hamartomas. Mayo Clin Proc. 1996; 71(1):14-20. DOI: 10.4065/71.1.14. View

15.

Ishibashi H, Akamatsu H, Kikuchi M, Sunamori M . Resection of endobronchial hamartoma by bronchoplasty and transbronchial endoscopic surgery. Ann Thorac Surg. 2003; 75(4):1300-2. DOI: 10.1016/s0003-4975(02)04624-6. View

16.

van den Bosch J, Wagenaar S, Corrin B, Elbers J, Knaepen P, Westermann C . Mesenchymoma of the lung (so called hamartoma): a review of 154 parenchymal and endobronchial cases. Thorax. 1987; 42(10):790-3. PMC: 460953. DOI: 10.1136/thx.42.10.790. View

17.

Sarioglu N, Susur A, Goksel T, Paksoy S, Erel F . An unexpected cause of hemoptysis: endobronchial lipomatous hamartoma. Med Arch. 2014; 68(1):65-6. PMC: 4272467. DOI: 10.5455/medarh.2014.68.65-66. View

18.

Abu Omar M, Ghanimeh M, Tylski E, Saettele T . Endobronchial hamartoma: a rare disease with more common presentation. BMJ Case Rep. 2016; 2016. PMC: 5129065. DOI: 10.1136/bcr-2016-216771. View

19.

Choi J, Yu C, Ryu Y, Jeon K, Choi K, Kwon O . The role of endoscopic surgery for completely obstructive endobronchial benign tumor. Korean J Intern Med. 2006; 21(1):15-9. PMC: 3891058. DOI: 10.3904/kjim.2006.21.1.15. View

20.

Schneider F, Winter H, Schwarz F, Niederhagen M, Arias-Herrera V, Martens E . Endobronchial lipomatous hamartoma: an incidental finding in a patient with atrial fibrillation-a case report. Case Rep Med. 2012; 2012:897581. PMC: 3295585. DOI: 10.1155/2012/897581. View