Tracheobronchial Tumors

Overview

Journal J Thorac Dis

Publisher AME Publishing Company

Specialty Pulmonary Medicine

Date 2017 Jan 10

PMID 28066620

Citations 35

Authors

Ruza Stevic

Branislava Milenkovic

Affiliations

Soon will be listed here.

Abstract

Tumors of trachea and bronchi are uncommon and can occur in the form of benign or low- and high-grade malignant tumors. Although tracheobronchial tumors (TBTs) represent only 0.6% of all pulmonary tumors, they are clinically significant. Delays in diagnosis of these tumors commonly occur because the signs and symptoms caused by these tumors are nonspecific and chest radiographs are often considered unremarkable. Therefore, novel radiological techniques and better access to flexible bronchoscopy enable detection of larger number of TBT. The purpose of this article is to provide a review of tracheal and bronchial tumors and discuss significant aspects of the different TBT with focus on clinical manifestations and diagnostic procedures.

Citing Articles

Artificial intelligence for the detection of airway nodules in chest CT scans.

Hendrix W, Hendrix N, Scholten E, van Ginneken B, Prokop M, Rutten M Eur Radiol. 2025; .

PMID: 40042650 DOI: 10.1007/s00330-025-11468-6.

Endobronchial Leiomyoma Presenting as Post-Obstructive Pneumonia.

Ng B, Low H, Abeed N, Sharil N, Osman R, Krishnasamy M Respirol Case Rep. 2025; 13(2):e70124.

PMID: 39975977 PMC: 11835759. DOI: 10.1002/rcr2.70124.

Comparison between community-acquired pneumonia and post-obstructive pneumonia associated with endobronchial tumors.

Yu W, Shi Y, Zheng Q, Chen J, Zhang X, Chen A BMC Pulm Med. 2024; 24(1):589.

PMID: 39609797 PMC: 11606229. DOI: 10.1186/s12890-024-03409-8.

A rare cause of bronchial obstruction: Endobronchial hamartoma case report.

Bouanani Z, Rais A, Benbrahim F, Akammar A, El Bouardi N, Haloua M Radiol Case Rep. 2024; 19(8):3473-3477.

PMID: 38872744 PMC: 11169075. DOI: 10.1016/j.radcr.2024.04.059.

Endoscopic submucosal dissection of endobronchial leiomyoma with a hybrid knife in an adolescent patient: a case report.

Wang Z, Hou G Front Oncol. 2023; 13:1288044.

PMID: 38044993 PMC: 10693421. DOI: 10.3389/fonc.2023.1288044.

References

Kadota N, Shinohara T, Machida H, Nakanishi H, Suehiro F, Toda H . Asymptomatic tracheal MALT lymphoma discovered on spirometric findings presenting with elevated respiratory resistance. BMC Res Notes. 2015; 8:223. PMC: 4467634. DOI: 10.1186/s13104-015-1218-5. View

Jugpal T, Garg A, Sethi G, Daga M, Kumar J . Multi-detector computed tomography imaging of large airway pathology: A pictorial review. World J Radiol. 2016; 7(12):459-74. PMC: 4697120. DOI: 10.4329/wjr.v7.i12.459. View

Miller R, Hyatt R . Evaluation of obstructing lesions of the trachea and larynx by flow-volume loops. Am Rev Respir Dis. 1973; 108(3):475-81. DOI: 10.1164/arrd.1973.108.3.475. View

Molina J, Aubry M, Lewis J, Wampfler J, Williams B, Midthun D . Primary salivary gland-type lung cancer: spectrum of clinical presentation, histopathologic and prognostic factors. Cancer. 2007; 110(10):2253-9. DOI: 10.1002/cncr.23048. View

Macchiarini P . Primary tracheal tumours. Lancet Oncol. 2006; 7(1):83-91. DOI: 10.1016/S1470-2045(05)70541-6. View

Bai C, Huang Y, Li Q, Xu H, Yao X, Liu Z . [Clinical features of endotracheal/endobronchial metastases: analysis of 62 cases]. Zhonghua Nei Ke Za Zhi. 2008; 46(10):806-9. View

England D, Hochholzer L . Truly benign "bronchial adenoma". Report of 10 cases of mucous gland adenoma with immunohistochemical and ultrastructural findings. Am J Surg Pathol. 1995; 19(8):887-99. DOI: 10.1097/00000478-199508000-00003. View

Miller R, Hyatt R . Obstructing lesions of the larynx and trachea: clinical and physiologic characteristics. Mayo Clin Proc. 1969; 44(3):145-61. View

Paganin F, Prevot M, Noel J, Frejeville M, Arvin-Berod C, Bourdin A . A solitary bronchial papilloma with unusual endoscopic presentation: case study and literature review. BMC Pulm Med. 2009; 9:40. PMC: 2734747. DOI: 10.1186/1471-2466-9-40. View

10.

Anrijs S, Weynand B, Pirson F, Rodenstein D, Pieters T . Chondroma: an uncommon case of bronchial tumor. J Bronchology Interv Pulmonol. 2012; 16(4):270-3. DOI: 10.1097/LBR.0b013e3181b64985. View

11.

Fink G, Krelbaum T, Yellin A, Bendayan D, Saute M, Glazer M . Pulmonary carcinoid: presentation, diagnosis, and outcome in 142 cases in Israel and review of 640 cases from the literature. Chest. 2001; 119(6):1647-51. DOI: 10.1378/chest.119.6.1647. View

12.

Compeau , Keshavjee . Management of Tracheal Neoplasms. Oncologist. 1996; 1(6):347-353. View

13.

Wilson R, Kirejczyk W . Pathological and radiological correlation of endobronchial neoplasms: Part I, Benign tumors. Ann Diagn Pathol. 1998; 1(1):31-46. DOI: 10.1016/s1092-9134(97)80007-x. View

14.

Nataf P, Gharbi N, Bourcereau J, Leroy-Ladurie F, Regnard J, Levasseur P . [Endobronchial lipomas. Apropos of 16 cases]. Rev Pneumol Clin. 1989; 45(5):203-5. View

15.

Cardillo G, Sera F, Di Martino M, Graziano P, Giunti R, Carbone L . Bronchial carcinoid tumors: nodal status and long-term survival after resection. Ann Thorac Surg. 2004; 77(5):1781-5. DOI: 10.1016/j.athoracsur.2003.10.089. View

16.

Bhatia K, Ellis S . Unusual lung tumours: an illustrated review of CT features suggestive of this diagnosis. Cancer Imaging. 2006; 6:72-82. PMC: 1693761. DOI: 10.1102/1470-7330.2006.0013. View

17.

Saoud M, Patil M, Dhillon S, Pokharel S, Picone A, Hennon M . Rare airway tumors: an update on current diagnostic and management strategies. J Thorac Dis. 2016; 8(8):1922-34. PMC: 4999752. DOI: 10.21037/jtd.2016.07.40. View

18.

Laroia A, Thompson B, Laroia S, van Beek Jr E . Modern imaging of the tracheo-bronchial tree. World J Radiol. 2010; 2(7):237-48. PMC: 2998855. DOI: 10.4329/wjr.v2.i7.237. View

19.

Wu C, Shepard J . Tracheal and airway neoplasms. Semin Roentgenol. 2013; 48(4):354-64. DOI: 10.1053/j.ro.2013.03.018. View

20.

Filosso P, Rena O, Donati G, Casadio C, Ruffini E, Papalia E . Bronchial carcinoid tumors: surgical management and long-term outcome. J Thorac Cardiovasc Surg. 2002; 123(2):303-9. DOI: 10.1067/mtc.2002.119886. View