DOPA-decarboxylase is Elevated in CSF, but Not Plasma, in Prodromal and De Novo Parkinson's Disease
Overview
Overview
Authors
Authors
Affiliations
Affiliations
Soon will be listed here.
Citing Articles
Bolsewig K, Willemse E, Sanchez-Juan P, Rabano A, Martinez M, Doecke J Nat Commun. 2025; 16(1):1139.
PMID: 39881147 PMC: 11779843. DOI: 10.1038/s41467-025-56293-z.
References
1.
van Rumund A, Pavelka L, Esselink R, Geurtz B, Wevers R, Mollenhauer B
. Peripheral decarboxylase inhibitors paradoxically induce aromatic L-amino acid decarboxylase. NPJ Parkinsons Dis. 2021; 7(1):29.
PMC: 7979935.
DOI: 10.1038/s41531-021-00172-z.
View
2.
Siderowf A, Concha-Marambio L, Lafontant D, Farris C, Ma Y, Urenia P
. Assessment of heterogeneity among participants in the Parkinson's Progression Markers Initiative cohort using α-synuclein seed amplification: a cross-sectional study. Lancet Neurol. 2023; 22(5):407-417.
PMC: 10627170.
DOI: 10.1016/S1474-4422(23)00109-6.
View
3.
Bloem B, Okun M, Klein C
. Parkinson's disease. Lancet. 2021; 397(10291):2284-2303.
DOI: 10.1016/S0140-6736(21)00218-X.
View
4.
Hadjiconstantinou M, Neff N
. Enhancing aromatic L-amino acid decarboxylase activity: implications for L-DOPA treatment in Parkinson's disease. CNS Neurosci Ther. 2008; 14(4):340-51.
PMC: 6494005.
DOI: 10.1111/j.1755-5949.2008.00058.x.
View
5.
Pereira J, Kumar A, Hall S, Palmqvist S, Stomrud E, Bali D
. DOPA decarboxylase is an emerging biomarker for Parkinsonian disorders including preclinical Lewy body disease. Nat Aging. 2023; 3(10):1201-1209.
PMC: 10570139.
DOI: 10.1038/s43587-023-00478-y.
View