Microbiome in Female Reproductive Health: Implications for Fertility and Assisted Reproductive Technologies

Overview

Journal Genomics Proteomics Bioinformatics

Specialty Biology

Date 2024 Jun 11

PMID 38862423

Authors

Liwen Xiao

Zhenqiang Zuo

Fangqing Zhao

Affiliations

Soon will be listed here.

Abstract

The microbiome plays a critical role in the process of conception and the outcomes of pregnancy. Disruptions in microbiome homeostasis in women of reproductive age can lead to various pregnancy complications, which significantly impact maternal and fetal health. Recent studies have associated the microbiome in the female reproductive tract (FRT) with assisted reproductive technology (ART) outcomes, and restoring microbiome balance has been shown to improve fertility in infertile couples. This review provides an overview of the role of the microbiome in female reproductive health, including its implications for pregnancy outcomes and ARTs. Additionally, recent advances in the use of microbial biomarkers as indicators of pregnancy disorders are summarized. A comprehensive understanding of the characteristics of the microbiome before and during pregnancy and its impact on reproductive health will greatly promote maternal and fetal health. Such knowledge can also contribute to the development of ARTs and microbiome-based interventions.

Citing Articles

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Surgical Technique and Fertility Outcomes: A Comprehensive Review of Open and Laparoscopic Cystectomy in Women of Reproductive Age.

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Navigating the Microbial Landscape: Understanding Dysbiosis in Human Genital Tracts and Its Impact on Fertility.

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Autophagy and Female Fertility: Mechanisms, Clinical Implications, and Emerging Therapies.

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