Prognostic Significance of Systemic Immune Inflammatory Index in NSCLC: a Meta-analysis
Overview
Authors
Affiliations
The aim of this meta-analysis was to investigate the relationship between the baseline systemic immune inflammatory index (SII) and prognosis in patients with NSCLC. The relation between pretreatment SII and overall survival, disease-free survival, cancer-specific survival, progression-free survival and recurrence-free survival in NSCLC patients was analyzed combined with hazard ratio and 95% CI. The results showed that high SII was significantly correlated with overall survival and progression-free survival of NSCLC patients, but not with disease-free survival, cancer-specific survival and recurrence-free survival. The study suggests that a higher SII has association with worse prognosis in NSCLC patients. CRD42022336270.
Uzun M, Gokcek S, Kaya E, Semiz H Discov Oncol. 2025; 16(1):317.
PMID: 40085163 DOI: 10.1007/s12672-025-02084-3.
Molecular subtypes and prognostic factors of lung large cell neuroendocrine carcinoma.
Liu T, Chen X, Mo S, Zhou T, Ma W, Chen G Transl Lung Cancer Res. 2024; 13(9):2222-2235.
PMID: 39430332 PMC: 11484736. DOI: 10.21037/tlcr-24-292.