Dataset of Finite Element Models of Normal and Deformed Thoracolumbar Spine

Overview

Journal Sci Data

Specialty Science

Date 2024 May 29

PMID 38811573

Authors

Morteza Rasouligandomani

Alejandro Del Arco

Francis Kiptengwer Chemorion

Marc-Antonio Bisotti

Fabio Galbusera

Jerome Noailly

Miguel A Gonzalez Ballester

Affiliations

Soon will be listed here.

Abstract

Adult spine deformity (ASD) is prevalent and leads to a sagittal misalignment in the vertebral column. Computational methods, including Finite Element (FE) Models, have emerged as valuable tools for investigating the causes and treatment of ASD through biomechanical simulations. However, the process of generating personalised FE models is often complex and time-consuming. To address this challenge, we present a dataset of FE models with diverse spine morphologies that statistically represent real geometries from a cohort of patients. These models are generated using EOS images, which are utilized to reconstruct 3D surface spine models. Subsequently, a Statistical Shape Model (SSM) is constructed, enabling the adaptation of a FE hexahedral mesh template for both the bone and soft tissues of the spine through mesh morphing. The SSM deformation fields facilitate the personalization of the mean hexahedral FE model based on sagittal balance measurements. Ultimately, this new hexahedral SSM tool offers a means to generate a virtual cohort of 16807 thoracolumbar FE spine models, which are openly shared in a public repository.

References

Wilke H, Herkommer A, Werner K, Liebsch C . In vitro analysis of the segmental flexibility of the thoracic spine. PLoS One. 2017; 12(5):e0177823. PMC: 5433776. DOI: 10.1371/journal.pone.0177823. View

Roberts S, Menage J, Urban J . Biochemical and structural properties of the cartilage end-plate and its relation to the intervertebral disc. Spine (Phila Pa 1976). 1989; 14(2):166-74. DOI: 10.1097/00007632-198902000-00005. View

Wilke H, Herkommer A, Werner K, Liebsch C . Analysis of the Intradiscal Pressure of the Thoracic Spine. Front Bioeng Biotechnol. 2020; 8:614. PMC: 7311578. DOI: 10.3389/fbioe.2020.00614. View

Iatridis J, Weidenbaum M, Setton L, Mow V . Is the nucleus pulposus a solid or a fluid? Mechanical behaviors of the nucleus pulposus of the human intervertebral disc. Spine (Phila Pa 1976). 1996; 21(10):1174-84. DOI: 10.1097/00007632-199605150-00009. View

Myronenko A, Song X . Point set registration: coherent point drift. IEEE Trans Pattern Anal Mach Intell. 2010; 32(12):2262-75. DOI: 10.1109/TPAMI.2010.46. View

Pearcy M . Stereo radiography of lumbar spine motion. Acta Orthop Scand Suppl. 1985; 212:1-45. DOI: 10.3109/17453678509154154. View

Calvo-Echenique A, Cegonino J, Perez Del Palomar A . Is there any advantage of using stand-alone cages? A numerical approach. Biomed Eng Online. 2019; 18(1):63. PMC: 6530002. DOI: 10.1186/s12938-019-0684-8. View

Roussouly P, Nnadi C . Sagittal plane deformity: an overview of interpretation and management. Eur Spine J. 2010; 19(11):1824-36. PMC: 2989270. DOI: 10.1007/s00586-010-1476-9. View

PEREY O . Fracture of the vertebral end-plate in the lumbar spine; an experimental biochemical investigation. Acta Orthop Scand Suppl. 1957; 25:1-101. DOI: 10.3109/ort.1957.28.suppl-25.01. View

10.

Noailly J, Wilke H, Planell J, Lacroix D . How does the geometry affect the internal biomechanics of a lumbar spine bi-segment finite element model? Consequences on the validation process. J Biomech. 2007; 40(11):2414-25. DOI: 10.1016/j.jbiomech.2006.11.021. View

11.

Guldberg R, Hollister S, Charras G . The accuracy of digital image-based finite element models. J Biomech Eng. 1999; 120(2):289-95. DOI: 10.1115/1.2798314. View

12.

Liu X, Sajda P, Saha P, Wehrli F, Guo X . Quantification of the roles of trabecular microarchitecture and trabecular type in determining the elastic modulus of human trabecular bone. J Bone Miner Res. 2006; 21(10):1608-17. PMC: 3225012. DOI: 10.1359/jbmr.060716. View

13.

Finley S, Brodke D, Spina N, DeDen C, Ellis B . FEBio finite element models of the human lumbar spine. Comput Methods Biomech Biomed Engin. 2018; 21(6):444-452. DOI: 10.1080/10255842.2018.1478967. View

14.

Heuer F, Schmidt H, Claes L, Wilke H . Stepwise reduction of functional spinal structures increase vertebral translation and intradiscal pressure. J Biomech. 2006; 40(4):795-803. DOI: 10.1016/j.jbiomech.2006.03.016. View

15.

Liebsch C, Graf N, Appelt K, Wilke H . The rib cage stabilizes the human thoracic spine: An in vitro study using stepwise reduction of rib cage structures. PLoS One. 2017; 12(6):e0178733. PMC: 5453693. DOI: 10.1371/journal.pone.0178733. View

16.

Newell N, Little J, Christou A, Adams M, Adam C, Masouros S . Biomechanics of the human intervertebral disc: A review of testing techniques and results. J Mech Behav Biomed Mater. 2017; 69:420-434. DOI: 10.1016/j.jmbbm.2017.01.037. View

17.

Pearcy M, Tibrewal S . Axial rotation and lateral bending in the normal lumbar spine measured by three-dimensional radiography. Spine (Phila Pa 1976). 1984; 9(6):582-7. DOI: 10.1097/00007632-198409000-00008. View

18.

Yilgor C, Sogunmez N, Boissiere L, Yavuz Y, Obeid I, Kleinstuck F . Global Alignment and Proportion (GAP) Score: Development and Validation of a New Method of Analyzing Spinopelvic Alignment to Predict Mechanical Complications After Adult Spinal Deformity Surgery. J Bone Joint Surg Am. 2017; 99(19):1661-1672. DOI: 10.2106/JBJS.16.01594. View

19.

Wilke H, Grundler S, Ottardi C, Mathew C, Schlager B, Liebsch C . In vitro analysis of thoracic spinal motion segment flexibility during stepwise reduction of all functional structures. Eur Spine J. 2019; 29(1):179-185. DOI: 10.1007/s00586-019-06196-7. View

20.

Picazo M, Magallon Baro A, Del Rio Barquero L, Di Gregorio S, Martelli Y, Romera J . 3-D Subject-Specific Shape and Density Estimation of the Lumbar Spine From a Single Anteroposterior DXA Image Including Assessment of Cortical and Trabecular Bone. IEEE Trans Med Imaging. 2018; 37(12):2651-2662. DOI: 10.1109/TMI.2018.2845909. View