Influenza Virus Genomic Surveillance, Arizona, USA, 2023-2024

Overview

Journal Viruses

Publisher MDPI

Specialty Microbiology

Date 2024 May 25

PMID 38793574

Authors

Rabia Maqsood

Matthew F Smith

LaRinda A Holland

Regan A Sullins

Steven C Holland

Michelle Tan

Gabrielle M Hernandez Barrera

Alexis W Thomas

Mario Islas

Joanna L Kramer

Lora Nordstrom

Mary Mulrow

Michael White

Vel Murugan

Efrem S Lim

Affiliations

Soon will be listed here.

Abstract

Influenza viruses are constantly evolving and are therefore monitored worldwide in the hope to reduce the burden of disease by annual updates to vaccine recommendations. We conducted genomic sequencing of 110 influenza A and 30 influenza B viruses from specimens collected between October 2023 and February 2024 in Arizona, USA. We identified mutations in the hemagglutinin (HA) antigenic sites as well as the neuraminidase (NA) gene in our samples. We also found no unique HA and NA mutations in vaccinated yet influenza-infected individuals. Real-time genomic sequencing surveillance is important to ensure influenza vaccine effectiveness.

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