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Chromosomal Localization of the Human Alpha 1-antitrypsin Gene (PI) to 14q31-32

Overview
Journal Am J Hum Genet
Publisher Cell Press
Specialty Genetics
Date 1985 Sep 1
PMID 3876766
Citations 21
Authors
W T Schroeder
M F Miller
S L Woo
G F Saunders
Affiliations
Soon will be listed here.
Abstract

In situ hybridization of a recombinant cDNA probe containing the human alpha 1-antitrypsin gene to metaphase chromosomes demonstrated significant hybridization to chromosomal segment 14q31-32. A high percentage of cells analyzed (31%) displayed labeling on chromosome 14. Of all labeled sites on chromosome 14, 60% were found on segment 14q31-32. These results refine the previous assignment of the human alpha 1-antitrypsin gene to segment 14q24.1-32.1.

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