» Articles » PMID: 38765606

Visualizing Metagenomic and Metatranscriptomic Data: A Comprehensive Review

Abstract

The fields of Metagenomics and Metatranscriptomics involve the examination of complete nucleotide sequences, gene identification, and analysis of potential biological functions within diverse organisms or environmental samples. Despite the vast opportunities for discovery in metagenomics, the sheer volume and complexity of sequence data often present challenges in processing analysis and visualization. This article highlights the critical role of advanced visualization tools in enabling effective exploration, querying, and analysis of these complex datasets. Emphasizing the importance of accessibility, the article categorizes various visualizers based on their intended applications and highlights their utility in empowering bioinformaticians and non-bioinformaticians to interpret and derive insights from meta-omics data effectively.

Citing Articles

Unveiling the potential of bioslurry and biogenic ZnO nanoparticles formulation as significant bionanofertilizer by ameliorating rhizospheric microbiome of Vigna radiata.

Singh A, Chauhan R, Prasad R, Agrawal A, Sah P, Goel A Int Microbiol. 2025; .

PMID: 40032755 DOI: 10.1007/s10123-025-00649-4.

References
1.
Wick R, Schultz M, Zobel J, Holt K . Bandage: interactive visualization of de novo genome assemblies. Bioinformatics. 2015; 31(20):3350-2. PMC: 4595904. DOI: 10.1093/bioinformatics/btv383. View

2.
Suzek B, Wang Y, Huang H, McGarvey P, Wu C . UniRef clusters: a comprehensive and scalable alternative for improving sequence similarity searches. Bioinformatics. 2014; 31(6):926-32. PMC: 4375400. DOI: 10.1093/bioinformatics/btu739. View

3.
Lin H, Liao Y . Accurate binning of metagenomic contigs via automated clustering sequences using information of genomic signatures and marker genes. Sci Rep. 2016; 6:24175. PMC: 4828714. DOI: 10.1038/srep24175. View

4.
Sukumaran J, Holder M . DendroPy: a Python library for phylogenetic computing. Bioinformatics. 2010; 26(12):1569-71. DOI: 10.1093/bioinformatics/btq228. View

5.
Kokoli M, Karatzas E, Baltoumas F, Schneider R, Pafilis E, Paragkamian S . Arena3D: interactive 3D visualization of multilayered networks supporting multiple directional information channels, clustering analysis and application integration. NAR Genom Bioinform. 2023; 5(2):lqad053. PMC: 10227371. DOI: 10.1093/nargab/lqad053. View