» Articles » PMID: 38736949

Eosinophilic Orbital Myositis Superseding Ocular Myasthenia

Overview
Specialty Rheumatology
Date 2024 May 13
PMID 38736949
Authors
Affiliations
Soon will be listed here.
Abstract

Various muscles can be involved in idiopathic eosinophilic myositis (IEM), with the ocular muscles being notably affected. Ocular eosinophilic myositis is a rare condition that typically affects the rectus muscles. A tissue biopsy stands as the gold standard for diagnosis. Different subtypes exist based on the extent of eosinophilic infiltration. Limited data is available about treatment, although glucocorticoids have shown successful outcomes. We present the case of a 60-year-old man who, a few years after being diagnosed with ocular myasthenia gravis, was diagnosed through a tissue biopsy with ocular eosinophilic myositis. Treatment with oral glucocorticoids significantly improved his symptoms.

References
1.
Toquet C, Hamidou M, Renaudin K, Jarry A, Foulc P, Barbarot S . In situ immunophenotype of the inflammatory infiltrate in eosinophilic fasciitis. J Rheumatol. 2003; 30(8):1811-5. View

2.
Fermon C, Authier F, Gallay L . Idiopathic eosinophilic myositis: a systematic literature review. Neuromuscul Disord. 2022; 32(2):116-124. DOI: 10.1016/j.nmd.2021.10.003. View

3.
Fermon C, Lessard L, Fenouil T, Meyer A, Faruch-Bilfeld M, Robert M . Revisiting idiopathic eosinophilic myositis: towards a clinical-pathological continuum from the muscle to the fascia and skin. Rheumatology (Oxford). 2022; 62(6):2220-2229. PMC: 10234208. DOI: 10.1093/rheumatology/keac556. View

4.
Ishida Y, Hayashi M, Higaki A, Matsumoto K, Iikura Y, Ishikawa J . Hypereosinophilic syndrome with generalized myasthenia gravis. J Pediatr. 1996; 128(3):369-72. DOI: 10.1016/s0022-3476(96)70284-6. View

5.
Schroder T, Fuchss J, Schneider I, Stoltenburg-Didinger G, Hanisch F . Eosinophils in hereditary and inflammatory myopathies. Acta Myol. 2014; 32(3):148-53. PMC: 4006278. View