» Articles » PMID: 38707030

Atypical Manifestation of Acute Myocardial Infarction (AMI) in a Vicenarian Woman With Polycystic Ovary Syndrome (PCOS) Undergoing Assisted Reproductive Technology (ART) Treatment: A Case Report

Overview
Journal Cureus
Date 2024 May 6
PMID 38707030
Authors
Affiliations
Soon will be listed here.
Abstract

Polycystic ovary syndrome (PCOS) is a prevalent endocrinological disorder affecting women of reproductive age, characterized by hormonal imbalances leading to metabolic and reproductive dysregulations. Acute myocardial infarction (AMI) represents a critical cardiovascular event, traditionally observed in older populations but increasingly identified in younger individuals with diverse medical backgrounds. The pursuit of assisted reproductive technology (ART) by women with PCOS to address infertility may further complicate cardiovascular risks due to the exogenous hormonal manipulations involved. This case report delineates a rare presentation of AMI in a 27-year-old vicenarian woman with PCOS undergoing ART treatment. Despite the absence of conventional cardiovascular risk factors, the patient exhibited typical symptoms and diagnostic features of AMI. Prompt recognition and intervention facilitated successful management and favorable outcomes. This case underscores the importance of considering atypical cardiovascular presentations in young women with complex medical histories, necessitating heightened awareness among healthcare providers. Multidisciplinary collaboration is imperative for comprehensive risk assessment, prevention, and tailored management strategies in this population. Further research is warranted to elucidate the intricate interplay between PCOS, ART, and cardiovascular outcomes, thereby optimizing clinical care and enhancing reproductive outcomes in this vulnerable cohort. An enhanced understanding of these relationships is essential for guiding evidence-based interventions aimed at mitigating cardiovascular risks and improving overall health outcomes in women with PCOS undergoing fertility treatments.

References
1.
Tchaikovski S, Rosing J . Mechanisms of estrogen-induced venous thromboembolism. Thromb Res. 2010; 126(1):5-11. DOI: 10.1016/j.thromres.2010.01.045. View

2.
Teede H, Deeks A, Moran L . Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan. BMC Med. 2010; 8:41. PMC: 2909929. DOI: 10.1186/1741-7015-8-41. View

3.
Mandal S, Pradhan R, Mols Kowalczewski B . Atypical Presentation of Myocardial Infarction in a Young Patient With Polycystic Ovarian Syndrome. Cureus. 2020; 12(7):e9494. PMC: 7458705. DOI: 10.7759/cureus.9494. View

4.
Rosenthal L, Bonder J . Successful Natural Pregnancy Using Whole Systems Traditional Chinese Medicine in a Complex Anovulatory Patient After Multiple Unsuccessful Fertilization Treatments: A Case Report. Med Acupunct. 2019; 31(5):304-309. PMC: 6795270. DOI: 10.1089/acu.2019.1388. View

5.
Guan C, Zahid S, Minhas A, Ouyang P, Vaught A, Baker V . Polycystic ovary syndrome: a "risk-enhancing" factor for cardiovascular disease. Fertil Steril. 2022; 117(5):924-935. DOI: 10.1016/j.fertnstert.2022.03.009. View