Seed Oil-A Valuable Source of Lipid-Soluble Components with DNA Protective and Antiproliferative Activities

Overview

Journal Foods

Specialty Biotechnology

Date 2024 Apr 27

PMID 38672940

Authors

Tsvetelina Andonova

Zhana Petkova

Olga Teneva

Ginka Antova

Elena Apostolova

Samir Naimov

Tsvetelina Mladenova

Iliya Slavov

Ivanka Dimitrova-Dyulgerova

Affiliations

Soon will be listed here.

Abstract

The present study is focused on the chemical and lipid composition of seed oil of the European ornamental and invasive wood plant (Simaroubaceae). Total lipids, proteins, carbohydrates, ash, and moisture in the seeds were determined. A high yield of glyceride oil (30.7%) was found, as well as a high content of fibers (29.6%) and proteins (18.7%). Physicochemical properties of the oil define it as semi-dry (129.4 g I/100 g Iodine value) with oxidative stability, refractive index, saponification value, and relative density similar to widely used oils with nutritional value and health benefits. The composition of the seed oil was determined chromatographically. Unsaturated fatty acids (95.3%) predominated in the seed oil, of which linoleic acid (48.6%) and oleic acid (44.8%) were the major ones. The main lipid-soluble bioactive components were -sitosterol (72.6%), -tocopherol (74.6%), phosphatidylinositol (29.5%), and phosphatidic acids (25.7%). The proven in vitro DNA-protective ability of seed oil is reported for the first time. The seed oil exhibited a weak antiproliferative effect on HT-29 and PC3 tumor cell lines and showed no cytotoxicity on the BALB/c 3T3 cell line. In brief, the present study reveals that seed oil can be used as a healthy food.

Citing Articles

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PMID: 38790860 PMC: 11121622. DOI: 10.3390/foods13101560.

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