Potential Antioxidant and Anti-inflammatory Activity of Extract Mediated Phytosynthesis of MnO Nanoparticles

The present research work describes the phyto-synthesis of Manganese dioxide nanoparticles (MnONPs) from the reduction of potassium permanganate using () plant extract. From the literature review, we clearly understood the plant has anti-inflammatory activity. Manganese dioxides are important materials due to their wide range of applications. Their increased surface area gives them distinct capabilities, as it increases their mechanical, magnetic, optical, and catalytic qualities, allowing them to be used in more pharmaceutical applications. A detailed review of literature highlighting the issues related to this present work and its knowledge gap that none of the inflammatory activities had been done by MnO NPs synthesized from plant extract. So we selected this study. The product MnO NPs showed the wavelength centre at 370 nm and was monitored by UV-Vis spectra. The wave number around 600 cm has to the occurrence of O-Mn-O bonds of pure MnO confirmed by FTIR spectroscopy. Transmission electron microscopy images showed the morphology of MnO NPs as spherical-shaped particles with average sizes at 7.5 nm. The selected area electron diffraction analysis exhibits the crystalline nature of MnO NPs. The obtained MnO NPs showed potential antioxidant and anti-inflammatory activity was compared to the plant extract. The synthesized MnO NPs have a large number of potential applications in the field of pharmaceutical industries. In the future, we isolate the phytocompounds present in the plant extract and conduct a study against corona virus. MnO produces manganese (III) oxide and oxygen, which increases fire hazard. But further research is required to understand their environmental behaviour and safety.