Visible-Light-Driven Decarboxylative Coupling of 2-Indazoles with α-Keto Acids Without Photocatalysts and Oxidants

Overview

Journal J Org Chem

Publisher American Chemical Society

Specialty Chemistry

Date 2024 Apr 20

PMID 38642058

Authors

Mengyu Niu

Chen Yang

Mingzhu Leng

Qun Cao

Meichao Li

Zhenlu Shen

Affiliations

Soon will be listed here.

Abstract

An efficient synthesis of functionalized 3-acyl-2-indazoles via visible-light-induced self-catalyzed energy transfer was developed. This method utilized a self-catalyzed energy transfer process between 2-indazoles and α-keto acids, offering advantages like absence of photosensitizers, metal catalysts, and strong oxidants, broad substrate compatibility, and operational simplicity under mild conditions.

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