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Mutations in the Splicing Factor SF3B1 Are Linked to Frequent Emergence of HLA-DR Monocytes in Lower-risk Myelodysplastic Neoplasms

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References
1.
Huber S, Haferlach T, Meggendorfer M, Hutter S, Hoermann G, Baer C . SF3B1 mutated MDS: Blast count, genetic co-abnormalities and their impact on classification and prognosis. Leukemia. 2022; 36(12):2894-2902. PMC: 9712089. DOI: 10.1038/s41375-022-01728-5. View

2.
Lieu Y, Liu Z, Ali A, Wei X, Penson A, Zhang J . SF3B1 mutant-induced missplicing of MAP3K7 causes anemia in myelodysplastic syndromes. Proc Natl Acad Sci U S A. 2021; 119(1). PMC: 8740767. DOI: 10.1073/pnas.2111703119. View

3.
Clough C, Pangallo J, Sarchi M, Ilagan J, North K, Bergantinos R . Coordinated missplicing of TMEM14C and ABCB7 causes ring sideroblast formation in SF3B1-mutant myelodysplastic syndrome. Blood. 2021; 139(13):2038-2049. PMC: 8972092. DOI: 10.1182/blood.2021012652. View

4.
Mortera-Blanco T, Dimitriou M, Woll P, Karimi M, Elvarsdottir E, Conte S . -initiating mutations in MDS-RSs target lymphomyeloid hematopoietic stem cells. Blood. 2017; 130(7):881-890. PMC: 5572789. DOI: 10.1182/blood-2017-03-776070. View

5.
Platzbecker U, Germing U, Gotze K, Kiewe P, Mayer K, Chromik J . Luspatercept for the treatment of anaemia in patients with lower-risk myelodysplastic syndromes (PACE-MDS): a multicentre, open-label phase 2 dose-finding study with long-term extension study. Lancet Oncol. 2017; 18(10):1338-1347. DOI: 10.1016/S1470-2045(17)30615-0. View