Exosomes Derived from Mesenchymal Stem Cells in Diabetes and Diabetic Complications

Overview

Journal Cell Death Dis

Specialties Cell Biology
General Medicine

Date 2024 Apr 17

PMID 38632264

Authors

Yu-Rui Jiao

Kai-Xuan Chen

Xiang Tang

Yu-Long Tang

Hai-Lin Yang

Yu-Long Yin

Chang-Jun Li

Affiliations

Soon will be listed here.

Abstract

Diabetes, a group of metabolic disorders, constitutes an important global health problem. Diabetes and its complications place a heavy financial strain on both patients and the global healthcare establishment. The lack of effective treatments contributes to this pessimistic situation and negative outlook. Exosomes released from mesenchymal stromal cells (MSCs) have emerged as the most likely new breakthrough and advancement in treating of diabetes and diabetes-associated complication due to its capacity of intercellular communication, modulating the local microenvironment, and regulating cellular processes. In the present review, we briefly outlined the properties of MSCs-derived exosomes, provided a thorough summary of their biological functions and potential uses in diabetes and its related complications.

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