Die Wechselwirkung Mit Ribosomalen Proteinen Begleitet Die Stressinduktion Des Wirkstoffkandidaten BOLD-100/KP1339 Im Endoplasmatischen Retikulum
Overview
Overview
Authors
Authors
Affiliations
Affiliations
Soon will be listed here.
Citing Articles
Neuditschko B, Legin A, Baier D, Schintlmeister A, Reipert S, Wagner M Angew Chem Weinheim Bergstr Ger. 2024; 133(10):5121-5126.
PMID: 38505777 PMC: 10947255. DOI: 10.1002/ange.202015962.
Highly Cytotoxic Molybdenocenes with Strong Metabolic Effects Inhibit Tumour Growth in Mice.
Fuchs V, Cseh K, Hejl M, Vician P, Neuditschko B, Meier-Menches S Chemistry. 2022; 29(4):e202202648.
PMID: 36222279 PMC: 10099754. DOI: 10.1002/chem.202202648.
References
1.
Hong M, Lin M, Huang J, Baumeister P, Hakre S, Roy A
. Transcriptional regulation of the Grp78 promoter by endoplasmic reticulum stress: role of TFII-I and its tyrosine phosphorylation. J Biol Chem. 2005; 280(17):16821-8.
DOI: 10.1074/jbc.M413753200.
View
2.
Meier-Menches S, Zappe K, Bileck A, Kreutz D, Tahir A, Cichna-Markl M
. Time-dependent shotgun proteomics revealed distinct effects of an organoruthenium prodrug and its activation product on colon carcinoma cells. Metallomics. 2018; 11(1):118-127.
DOI: 10.1039/c8mt00152a.
View
3.
Burris H, Bakewell S, Bendell J, Infante J, Jones S, Spigel D
. Safety and activity of IT-139, a ruthenium-based compound, in patients with advanced solid tumours: a first-in-human, open-label, dose-escalation phase I study with expansion cohort. ESMO Open. 2017; 1(6):e000154.
PMC: 5548977.
DOI: 10.1136/esmoopen-2016-000154.
View
4.
Bytzek A, Koellensperger G, Keppler B, Hartinger C
. Biodistribution of the novel anticancer drug sodium trans-[tetrachloridobis(1H-indazole)ruthenate(III)] KP-1339/IT139 in nude BALB/c mice and implications on its mode of action. J Inorg Biochem. 2016; 160:250-5.
DOI: 10.1016/j.jinorgbio.2016.02.037.
View
5.
Babak M, Meier S, Huber K, Reynisson J, Legin A, Jakupec M
. Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action. Chem Sci. 2018; 6(4):2449-2456.
PMC: 5647740.
DOI: 10.1039/c4sc03905j.
View