Age-wise Examination of the Association of Obesity Based on Body Mass Index and Waist Circumference with Metabolic Diseases in Comprehensive Health Checkup Participants
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Aim: Body mass index and waist circumference are used for obesity diagnosis and screening of visceral fat; however, their evidence in older adults is insufficient. This study investigated the age-specific association of body mass index and waist circumference with metabolic diseases, assessing their applicability as diagnostic criteria for individuals aged ≥65 years.
Methods: Analysis included 46,324 individuals aged ≥18 years, categorized into five age groups: 18-44, 45-54, 55-64, 65-74, and ≥75 years. Logistic regression analyses identified associations between obesity and metabolic diseases, stratified by age and sex.
Results: Men with obesity based on body mass index had a significantly high risk of hypertension, diabetes mellitus, and dyslipidemia across all age groups (all, < 0.05). Obesity based on waist circumference was significantly positively associated with all metabolic diseases (all, < 0.05). Women with obesity based on body mass index and waist circumference had a significantly high risk of all metabolic diseases across all age groups (all, < 0.05), except for diabetes mellitus in individuals aged ≥75 years.
Conclusions: Participants with obesity based on body mass index and waist circumference exhibited a high risk of hypertension, diabetes mellitus, and dyslipidemia among those aged 18-74 years and men aged ≥75 years. This study contributes to the early prevention and control of metabolic diseases.
Franchi M, Fiorini G, Conflitti C, Schibuola F, Rigamonti A, Sartorio A Healthcare (Basel). 2024; 12(23).
PMID: 39684947 PMC: 11641085. DOI: 10.3390/healthcare12232326.
Yamamoto Y, Ikeue K, Kanasaki M, Yamakage H, Satoh-Asahara N, Masuda I Obes Sci Pract. 2024; 10(2):e746.
PMID: 38501152 PMC: 10946448. DOI: 10.1002/osp4.746.