Exploring the Complex Interplay: Gut Microbiome, Stress, and Leptospirosis

Overview

Journal Front Microbiol

Specialty Microbiology

Date 2024 Mar 13

PMID 38476949

Authors

Pavlo Petakh

Valentyn Oksenych

Iryna Kamyshna

Iryna Boisak

Katerina Lyubomirskaya

Oleksandr Kamyshnyi

Affiliations

Soon will be listed here.

Abstract

Leptospirosis, a re-emerging zoonotic disease, remains a significant global health concern, especially amid floods and disasters such as the Kakhovka Dam destruction. As is known, the stress that occurs in the conditions of military conflicts among civilian and military personnel significantly affects susceptibility to infectious diseases and possibly even influences their course. This review aims to explore how the gut microbiome and stress mediators (such as catecholamines and corticosteroids) might impact the leptospirosis disease course. The review opens new horizons for research by elucidating the connections between the gut microbiome, stress, and leptospirosis.

Citing Articles

Geographical factors and air raid alarms influence leptospirosis epidemiology in Ukraine (2018-2023).

Petakh P, Huber W, Kamyshnyi O One Health. 2024; 19:100944.

PMID: 39679281 PMC: 11639380. DOI: 10.1016/j.onehlt.2024.100944.

Microplastics and human health: unveiling the gut microbiome disruption and chronic disease risks.

Bora S, Gogoi R, Sharma M, Anshu , Borah M, Deka P Front Cell Infect Microbiol. 2024; 14():1492759.

PMID: 39669275 PMC: 11635378. DOI: 10.3389/fcimb.2024.1492759.

Surveillance of human leptospirosis infections in Ukraine between 2018 and 2023.

Petakh P, Tymchyk V, Kamyshnyi O Front Public Health. 2024; 12:1394781.

PMID: 38932783 PMC: 11199720. DOI: 10.3389/fpubh.2024.1394781.

Comprehensive Analysis of Antiphage Defense Mechanisms: Serovar-Specific Patterns.

Petakh P, Oksenych V, Khovpey Y, Kamyshnyi O Antibiotics (Basel). 2024; 13(6).

PMID: 38927188 PMC: 11201134. DOI: 10.3390/antibiotics13060522.

Molecular mechanisms and therapeutic possibilities of short-chain fatty acids in posttraumatic stress disorder patients: a mini-review.

Petakh P, Duve K, Oksenych V, Behzadi P, Kamyshnyi O Front Neurosci. 2024; 18:1394953.

PMID: 38887367 PMC: 11182003. DOI: 10.3389/fnins.2024.1394953.

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