Similar Rates of Reoperation for Neuroma After Transtibial Amputations with and Without Targeted Muscle Reinnervation

Overview

Journal OTA Int

Date 2024 Mar 4

PMID 38433988

Authors

Thomas P Smith

Daniel J Cognetti

Alyssa Cook

Thomas B Lynch

Joseph F Alderete

Dustin O Lybeck

Thomas C Dowd

Affiliations

Soon will be listed here.

Abstract

Objective: To compare the rates of revision surgery for symptomatic neuromas in patients undergoing primary transtibial amputations with and without targeted muscle reinnervation (TMR).

Design: Retrospective cohort study.

Setting: Level I trauma hospital and tertiary military medical center.

Patients/participants: Adult patients undergoing transtibial amputations with and without TMR.

Intervention: Transtibial amputation with targeted muscle reinnervation.

Main Outcome Measurements: Reoperation for symptomatic neuroma.

Results: During the study period, there were 112 primary transtibial amputations performed, 29 with TMR and 83 without TMR. Over the same period, there were 51 revision transtibial amputations performed, including 23 (21%) in the patients undergoing primary transtibial amputation at the study institution. The most common indications for revision surgery were wound breakdown/dehiscence (42%, n = 25), followed by symptomatic neuroma 18% (n = 9/51) and infection/osteomyelitis (17%, n = 10) as the most common indications. However, of the patients undergoing primary amputation at the study's institution, there was no difference in reoperation rates for neuroma when comparing the TMR group (3.6%, n = 1/28) and no TMR group (4.0%, n = 3/75) ( = 0.97).

Conclusions: Symptomatic neuroma is one of the most common reasons for revision amputation; however, this study was unable to demonstrate a difference in revision surgery rates for neuroma for patients undergoing primary transtibial amputation with or without targeted muscle reinnervation.

Level Of Evidence: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.

Citing Articles

Curative and preemptive treatment of amputee pain by targeted muscle reinnervation: experience from a French military trauma center.

Mathieu L, Redais C, Diner C, Lemaire-Petit A, Milaire A, Chataigneau A Eur J Trauma Emerg Surg. 2025; 51(1):37.

PMID: 39853391 DOI: 10.1007/s00068-024-02701-w.

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