Antimicrobial Activity of Polycaprolactone Nanofiber Coated with Lavender and Neem Oil Nanoemulsions Against Airborne Bacteria

Overview

Journal Membranes (Basel)

Date 2024 Feb 23

PMID 38392663

Authors

Md Mahfuzur Rahman

Hari Kotturi

Sadegh Nikfarjam

Kanika Bhargava

Nagib Ahsan

Morshed Khandaker

Affiliations

Soon will be listed here.

Abstract

The development of efficient, eco-friendly antimicrobial agents for air purification and disinfection addresses public health issues connected to preventing airborne pathogens. Herein, the antimicrobial activity of a nanoemulsion (control, 5%, 10%, and 15%) containing neem and lavender oils with polycaprolactone (PCL) was investigated against airborne bacteria, including , , and . Various parameters such as the physicochemical properties of the nanoemulsion, pH, droplet size, the polydispersity index (PDI), the minimum inhibitory concentration (MIC), the minimum bacterial concentration (MBC), and the color measurement of the emulsion have been evaluated and optimized. Our results showed that the antimicrobial activity of PCL combined with neem and lavender oil was found to be the highest MIC and MBC against all tested bacteria. The droplet sizes for lavender oil are 21.86-115.15 nm, the droplet sizes for neem oil are 23.92-119.15 nm, and their combination is 25.97-50.22 nm. The range of pH and viscosity of nanoemulsions of various concentrations was found to be 5.8 to 6.6 pH and 0.372 to 2.101 cP. This study highlights the potential of nanotechnology in harnessing the antimicrobial properties of natural essential oils, paving the way for innovative and sustainable solutions in the fight against bacterial contamination.

Citing Articles

Chemical Characterization and Antimicrobial Activity of Essential Oils and Nanoemulsions of and .

Dos Santos R, Matos B, Freire D, da Silva F, do Prado B, Gomes K Antibiotics (Basel). 2025; 14(1.

PMID: 39858378 PMC: 11763297. DOI: 10.3390/antibiotics14010093.

References

Pertegal V, Riquelme E, Lozano-Serra J, Canizares P, Rodrigo M, Saez C . Cleaning technologies integrated in duct flows for the inactivation of pathogenic microorganisms in indoor environments: A critical review of recent innovations and future challenges. J Environ Manage. 2023; 345:118798. DOI: 10.1016/j.jenvman.2023.118798. View

Elkalla E, Khizar S, Tarhini M, Lebaz N, Zine N, Jaffrezic-Renault N . Core-shell micro/nanocapsules: from encapsulation to applications. J Microencapsul. 2023; 40(3):125-156. DOI: 10.1080/02652048.2023.2178538. View

Duan J, Nie R, Du J, Sun H, Liu G . Effect of Nanoemulsion Containing Enterocin GR17 and Cinnamaldehyde on Microbiological, Physicochemical and Sensory Properties and Shelf Life of Liquid-Smoked Salmon Fillets. Foods. 2023; 12(1). PMC: 9818589. DOI: 10.3390/foods12010078. View

Asghari F, Samiei M, Adibkia K, Akbarzadeh A, Davaran S . Biodegradable and biocompatible polymers for tissue engineering application: a review. Artif Cells Nanomed Biotechnol. 2016; 45(2):185-192. DOI: 10.3109/21691401.2016.1146731. View

Baghi F, Gharsallaoui A, Dumas E, Ghnimi S . Advancements in Biodegradable Active Films for Food Packaging: Effects of Nano/Microcapsule Incorporation. Foods. 2022; 11(5). PMC: 8909076. DOI: 10.3390/foods11050760. View

Hernandez-Garcia E, Vargas M, Gonzalez-Martinez C, Chiralt A . Biodegradable Antimicrobial Films for Food Packaging: Effect of Antimicrobials on Degradation. Foods. 2021; 10(6). PMC: 8228111. DOI: 10.3390/foods10061256. View

Benelli G, Pavoni L, Zeni V, Ricciardi R, Cosci F, Cacopardo G . Developing a Highly Stable Essential Oil Nanoemulsion for Managing . Nanomaterials (Basel). 2020; 10(9). PMC: 7559805. DOI: 10.3390/nano10091867. View

Uhljar L, Ambrus R . Electrospinning of Potential Medical Devices (Wound Dressings, Tissue Engineering Scaffolds, Face Masks) and Their Regulatory Approach. Pharmaceutics. 2023; 15(2). PMC: 9965305. DOI: 10.3390/pharmaceutics15020417. View

Ozogul Y, Karsli G, Durmus M, Yazgan H, Oztop H, McClements D . Recent developments in industrial applications of nanoemulsions. Adv Colloid Interface Sci. 2022; 304:102685. DOI: 10.1016/j.cis.2022.102685. View

10.

Kotturi H, Lopez-Davis C, Nikfarjam S, Kedy C, Byrne M, Barot V . Incorporation of Mycobacteriophage Fulbright into Polycaprolactone Electrospun Nanofiber Wound Dressing. Polymers (Basel). 2022; 14(10). PMC: 9143337. DOI: 10.3390/polym14101948. View

11.

Khandaker M, Progri H, Arasu D, Nikfarjam S, Shamim N . Use of Polycaprolactone Electrospun Nanofiber Mesh in a Face Mask. Materials (Basel). 2021; 14(15). PMC: 8347738. DOI: 10.3390/ma14154272. View

12.

Akdemir Evrendilek G . Empirical prediction and validation of antibacterial inhibitory effects of various plant essential oils on common pathogenic bacteria. Int J Food Microbiol. 2015; 202:35-41. DOI: 10.1016/j.ijfoodmicro.2015.02.030. View

13.

Nair A, Mallya R, Suvarna V, Khan T, Momin M, Omri A . Nanoparticles-Attractive Carriers of Antimicrobial Essential Oils. Antibiotics (Basel). 2022; 11(1). PMC: 8773333. DOI: 10.3390/antibiotics11010108. View

14.

Parvekar P, Palaskar J, Metgud S, Maria R, Dutta S . The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of silver nanoparticles against . Biomater Investig Dent. 2020; 7(1):105-109. PMC: 7470068. DOI: 10.1080/26415275.2020.1796674. View

15.

Predoi D, Groza A, Iconaru S, Predoi G, Barbuceanu F, Guegan R . Properties of Basil and Lavender Essential Oils Adsorbed on the Surface of Hydroxyapatite. Materials (Basel). 2018; 11(5). PMC: 5978029. DOI: 10.3390/ma11050652. View

16.

Cushnie T, Cushnie B, Echeverria J, Fowsantear W, Thammawat S, Dodgson J . Bioprospecting for Antibacterial Drugs: a Multidisciplinary Perspective on Natural Product Source Material, Bioassay Selection and Avoidable Pitfalls. Pharm Res. 2020; 37(7):125. DOI: 10.1007/s11095-020-02849-1. View