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The Potential Effects of Dietary Antioxidants in Obesity: A Comprehensive Review of the Literature

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Specialty Health Services
Date 2024 Feb 23
PMID 38391792
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Abstract

Obesity has become a global health concern, with its prevalence steadily increasing in recent decades. It is associated with numerous health complications, including cardiovascular diseases, diabetes, and certain types of cancer. The aetiology of obesity is multifactorial, involving genetic, environmental, and lifestyle factors. In recent years, oxidative stress has emerged as a potential contributor to obesity and its related metabolic disorders. Dietary antioxidants, which can counteract oxidative stress, have gained significant attention for their potential role in preventing and managing obesity. This comprehensive review aims to explore the impact of dietary antioxidants on obesity and its associated metabolic dysregulations, discussing the underlying mechanisms and highlighting the potential therapeutic implications.

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References
1.
Mitchell N, Catenacci V, Wyatt H, Hill J . Obesity: overview of an epidemic. Psychiatr Clin North Am. 2011; 34(4):717-32. PMC: 3228640. DOI: 10.1016/j.psc.2011.08.005. View

2.
Sies H, Jones D . Reactive oxygen species (ROS) as pleiotropic physiological signalling agents. Nat Rev Mol Cell Biol. 2020; 21(7):363-383. DOI: 10.1038/s41580-020-0230-3. View

3.
Saponaro C, Gaggini M, Carli F, Gastaldelli A . The Subtle Balance between Lipolysis and Lipogenesis: A Critical Point in Metabolic Homeostasis. Nutrients. 2015; 7(11):9453-74. PMC: 4663603. DOI: 10.3390/nu7115475. View

4.
Chaves G, Pereira S, Saboya C, Ramalho A . Non-alcoholic fatty liver disease and its relationship with the nutritional status of vitamin A in individuals with class III obesity. Obes Surg. 2008; 18(4):378-85. DOI: 10.1007/s11695-007-9361-2. View

5.
Aseervatham G, Sivasudha T, Jeyadevi R, Ananth D . Environmental factors and unhealthy lifestyle influence oxidative stress in humans--an overview. Environ Sci Pollut Res Int. 2013; 20(7):4356-69. DOI: 10.1007/s11356-013-1748-0. View