ACTUALITIES IN THE MANAGEMENT OF SECONDARY HYPERPARATHYROIDISM DUE TO CHRONIC KIDNEY DISEASE IN CHILDREN

Overview

Journal Acta Endocrinol (Buchar)

Specialty Endocrinology

Date 2024 Feb 15

PMID 38356968

Authors

M Gafencu

R M Steflea

Affiliations

Soon will be listed here.

Abstract

Pediatric chronic kidney disease (CKD) has a substantial global impact because is associated with notable morbidity. Secondary hyperparathyroidism (SPHT) frequently emerges as a complication in the early stages of renal insufficiency, it is an adaptive response to uphold mineral balance. It is a component of the chronic kidney disease-mineral and bone disorder (CKD-MBD). The development of SHPT in CKD involves multiple factors and it is important to understand them in order to properly manage it, starting with early diagnosis and continuing with proper treatment. In children with CKD and SHPT, the difficulty in case management is due to non-adherence to proper diet which makes it difficult for the pediatric nephrologist to manage the case. In this review we want to focus on new data regarding this CKD complication.

Citing Articles

Evaluating Neutrophil Gelatinase-Associated Lipocalin in Pediatric CKD: Correlations with Renal Function and Mineral Metabolism.

Steflea R, Stoicescu E, Aburel O, Horhat F, Vlad S, Bratosin F Pediatr Rep. 2024; 16(4):1099-1114.

PMID: 39728735 PMC: 11676301. DOI: 10.3390/pediatric16040094.

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