Traditional Uses, Phytochemistry, and Pharmacological Activities of : A Comprehensive Review
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Benth., also known as (Lour.) Spreng., is a perennial plant from the Lamiaceae family commonly found in tropical and warm regions of Africa, Asia, and Australia. Folk medicine commonly employs this remedy to address various ailments, including but not limited to asthma, headaches, skin disorders, coughs, constipation, colds, and fevers. Several phytoconstituents from various phytochemical classes, such as phenolics, terpenoids, phenolic acids, flavonoids, flavones, and tannins, have been identified in up to the present time. Numerous pharmacological properties of Coleus amboinicus crude extracts have been documented through both and in vivo studies, including but not limited to antitumor, antibacterial, antifungal, antiprotozoal, anti-inflammatory, antioxidant, antidiabetic, wound healing, analgesic, antirheumatic, and various other therapeutic effects. Due to its extensive history of traditional usage, the diverse array of bioactive phytochemicals, and numerous established pharmacological activities, is widely regarded as having significant potential for clinical applications and warrants further exploration, development, and exploitation through research. With this context, the present study gathers information on the occurrence, biological description, cultivation, and nutritional values of . Furthermore, it thoroughly discusses various phytoconstituents, along with their classes, present in , followed by detailed descriptions of their pharmacological activities based on recent literature.
Narayana S, Gowda B, Hani U, Shimu S, Paul K, Das A J Nanobiotechnology. 2024; 22(1):427.
PMID: 39030546 PMC: 11264527. DOI: 10.1186/s12951-024-02701-3.