Metabolic Changes in Pregnancy Relevant to Diabetes Mellitus

Overview

Journal Postgrad Med J

Publisher Oxford University Press

Specialty General Medicine

Date 1979 May 1

PMID 382168

Citations 8

Authors

T Lind

Affiliations

Soon will be listed here.

Abstract

The alterations in carbohydrate metabolism during pregnancy are discussed and possible mechanisms for these changes are put forward. It is stressed that the raised levels of plasma glucose, the enhanced response to insulin and the decreased tissue sensitivity to insulin are all features of normal pregnancy. It may be difficult to distinguish this from very early forms of diabetes mellitus during pregnancy, the detection of which is briefly considered.

Citing Articles

The glucose tolerance peak parameter revisited. Definition for a novel use in Gestational Diabetes Mellitus confirmation.

Ben Abdelhanin M J Diabetes Metab Disord. 2024; 23(1):1351-1357.

PMID: 38932791 PMC: 11196505. DOI: 10.1007/s40200-024-01432-4.

Meal Timing and Glycemic Control during Pregnancy-Is There a Link?.

Zhu S, Surampudi P, Field N, Chondronikola M Nutrients. 2021; 13(10).

PMID: 34684381 PMC: 8540614. DOI: 10.3390/nu13103379.

Prevalence of Gestational Diabetes Mellitus in urban and rural Tamil Nadu using IADPSG and WHO 1999 criteria (WINGS 6).

Bhavadharini B, Mahalakshmi M, Anjana R, Maheswari K, Uma R, Deepa M Clin Diabetes Endocrinol. 2017; 2:8.

PMID: 28702243 PMC: 5471800. DOI: 10.1186/s40842-016-0028-6.

Maternal cardiac metabolism in pregnancy.

Liu L, Arany Z Cardiovasc Res. 2014; 101(4):545-53.

PMID: 24448314 PMC: 3941596. DOI: 10.1093/cvr/cvu009.

Antenatal haemoglobin A1c and risk of large-for-gestational-age infants in a multi-ethnic cohort of women with gestational diabetes.

Katon J, Reiber G, Williams M, Yanez D, Miller E Paediatr Perinat Epidemiol. 2012; 26(3):208-17.

PMID: 22471680 PMC: 7442536. DOI: 10.1111/j.1365-3016.2012.01266.x.

References

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Lind T, Bell S, Gilmore E, Huisjes H, Schally A . Insulin disappearance rate in pregnant and non-pregnant women, and in non-pregnant women given GHRIH. Eur J Clin Invest. 1977; 7(1):47-52. DOI: 10.1111/j.1365-2362.1977.tb01569.x. View

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TOEPFER E, Mertz W, ROGINSKI E, Polansky M . Chromium in foods in relation to biological activity. J Agric Food Chem. 1973; 21(1):69-71. DOI: 10.1021/jf60185a008. View

Lind T, Billewicz W, Brown G . A serial study of changes occurring in the oral glucose tolerance test during pregnancy. J Obstet Gynaecol Br Commonw. 1973; 80(12):1033-9. DOI: 10.1111/j.1471-0528.1973.tb02976.x. View

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11.

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