Maternal Cardiac Metabolism in Pregnancy

Overview

Journal Cardiovasc Res

Specialty Cardiology & Vascular Diseases

Date 2014 Jan 23

PMID 24448314

Citations 51

Authors

Laura X Liu

Zolt Arany

Affiliations

Soon will be listed here.

Abstract

Pregnancy causes dramatic physiological changes in the expectant mother. The placenta, mostly foetal in origin, invades maternal uterine tissue early in pregnancy and unleashes a barrage of hormones and other factors. This foetal 'invasion' profoundly reprogrammes maternal physiology, affecting nearly every organ, including the heart and its metabolism. We briefly review here maternal systemic metabolic changes during pregnancy and cardiac metabolism in general. We then discuss changes in cardiac haemodynamic during pregnancy and review what is known about maternal cardiac metabolism during pregnancy. Lastly, we discuss cardiac diseases during pregnancy, including peripartum cardiomyopathy, and the potential contribution of aberrant cardiac metabolism to disease aetiology.

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