Changes in Gut Microbiota Associated with Parity in Large White Sows

Overview

Journal Animals (Basel)

Date 2024 Jan 11

PMID 38200843

Authors

Yage Bu

Lingli Feng

Di Xu

Shuai Zhang

Liang Liang

Jinglei Si

Yujie Lu

Qiaoling Liu

Gang Yan

Yubin Wang

Ganqiu Lan

Jing Liang

Affiliations

Soon will be listed here.

Abstract

As one of the most critical economic traits, the litter performance of sows is influenced by their parity. Some studies have indicated a connection between the gut microbiota and the litter performance of animals. In this study, we examined litter performance in 1363 records of different parities of Large White sows. We observed a marked decline in TNB (Total Number Born) and NBH (Number of Healthy Born) We observed a marked decline in TNB (Total Number Born) and NBH (Number of Healthy Born) among sows with parity 7 or higher. To gain a deeper understanding of the potential role of gut microbiota in this phenomenon, we conducted 16S rRNA amplicon sequencing of fecal DNA from 263 Large White sows at different parities and compared the changes in their gut microbiota with increasing parity. The results revealed that in comparison to sows with a parity from one to six, sows with a parity of seven or higher exhibited decreased alpha diversity in their gut microbiota. There was an increased proportion of pathogenic bacteria (such as , , and ) and a reduced proportion of SCFA-producing families (such as ), indicating signs of inflammatory aging. The decline in sow function may be one of the primary reasons for the reduction in their litter performance.

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