Surgical Radioguidance with Beta-emitting Radionuclides; Challenges and Possibilities: A Position Paper by the EANM

Overview

Journal Eur J Nucl Med Mol Imaging

Specialties Biophysics
Nuclear Medicine
Radiology

Date 2024 Jan 8

PMID 38189911

Authors

Pedro Fragoso Costa

Kuangyu Shi

Soren Holm

Sergi Vidal-Sicart

Tereza Kracmerova

Giovanni Tosi

Jan Grimm

Dimitris Visvikis

Wolfram H Knapp

Gopinath Gnanasegaran

Fijs W B van Leeuwen

Affiliations

Soon will be listed here.

Abstract

Radioguidance that makes use of β-emitting radionuclides is gaining in popularity and could have potential to strengthen the range of existing radioguidance techniques. While there is a strong tendency to develop new PET radiotracers, due to favorable imaging characteristics and the success of theranostics research, there are practical challenges that need to be overcome when considering use of β-emitters for surgical radioguidance. In this position paper, the EANM identifies the possibilities and challenges that relate to the successful implementation of β-emitters in surgical guidance, covering aspects related to instrumentation, radiation protection, and modes of implementation.

Citing Articles

First-in-human validation of a DROP-IN β-probe for robotic radioguided surgery: defining optimal signal-to-background discrimination algorithm.

Collamati F, Morganti S, van Oosterom M, Campana L, Ceci F, Luzzago S Eur J Nucl Med Mol Imaging. 2024; 51(10):3098-3108.

PMID: 38376805 PMC: 11300660. DOI: 10.1007/s00259-024-06653-6.

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