Vitamin E - a Scoping Review for Nordic Nutrition Recommendations 2023

Overview

Journal Food Nutr Res

Specialty Nutritional Sciences

Date 2024 Jan 8

PMID 38187798

Authors

Essi Hantikainen

Ylva Trolle Lagerros

Affiliations

Soon will be listed here.

Abstract

Current evidence suggests that dietary vitamin E (as α-tocopherol) intake has a beneficial role in preventing certain chronic diseases. In contrast, there is no clear evidence for the benefit of α-tocopherol supplements in a generally healthy population. Deficiency symptoms are rare and mainly occur due to genetic or other factors affecting α-tocopherol absorption and/or metabolism, rather than a low α-tocopherol intake. No qualified systematic review was identified by the NNR2023 project for updating the dietary reference values (DRV).

Citing Articles

Can the combination of proanthocyanidin and vitamin E or palm oil effectively protect enamel against in vitro erosive and abrasive challenges?.

da Silva Martins D, Boteon A, Ferreira A, Debortolli A, Grizzo I, Ionta F J Appl Oral Sci. 2024; 32:e20240100.

PMID: 39046065 PMC: 11321796. DOI: 10.1590/1678-7757-2024-0100.

References

Warensjo Lemming E, Pitsi T . The Nordic Nutrition Recommendations 2022 - food consumption and nutrient intake in the adult population of the Nordic and Baltic countries. Food Nutr Res. 2022; 66. PMC: 9199833. DOI: 10.29219/fnr.v66.8572. View

Traber M . Mechanisms for the prevention of vitamin E excess. J Lipid Res. 2013; 54(9):2295-306. PMC: 3735929. DOI: 10.1194/jlr.R032946. View

Traber M . Vitamin E regulatory mechanisms. Annu Rev Nutr. 2007; 27:347-62. DOI: 10.1146/annurev.nutr.27.061406.093819. View

Hoyer A, Christensen J, Arnesen E, Andersen R, Eneroth H, Erkkola M . The Nordic Nutrition Recommendations 2022 - prioritisation of topics for systematic reviews. Food Nutr Res. 2022; 65. PMC: 8897982. DOI: 10.29219/fnr.v65.7828. View

Loh H, Lim R, Lee K, Ooi C, Chuan D, Looi I . Effects of vitamin E on stroke: a systematic review with meta-analysis and trial sequential analysis. Stroke Vasc Neurol. 2020; 6(1):109-120. PMC: 8005911. DOI: 10.1136/svn-2020-000519. View

Hu X, Li S, Zhou L, Zhao M, Zhu X . Effect of vitamin E supplementation on uterine cervical neoplasm: A meta-analysis of case-control studies. PLoS One. 2017; 12(8):e0183395. PMC: 5567498. DOI: 10.1371/journal.pone.0183395. View

Traber M . Vitamin E inadequacy in humans: causes and consequences. Adv Nutr. 2014; 5(5):503-14. PMC: 4188222. DOI: 10.3945/an.114.006254. View

Curtis A, Bullen M, Piccenna L, McNeil J . Vitamin E supplementation and mortality in healthy people: a meta-analysis of randomised controlled trials. Cardiovasc Drugs Ther. 2014; 28(6):563-73. DOI: 10.1007/s10557-014-6560-7. View

. Proposed nutrient and energy intakes for the European community: a report of the Scientific Committee for Food of the European community. Nutr Rev. 1993; 51(7):209-12. DOI: 10.1111/j.1753-4887.1993.tb03106.x. View

10.

Fulan H, Changxing J, Baina W, Wencui Z, Chunqing L, Fan W . Retinol, vitamins A, C, and E and breast cancer risk: a meta-analysis and meta-regression. Cancer Causes Control. 2011; 22(10):1383-96. DOI: 10.1007/s10552-011-9811-y. View

11.

Constantinou C, Charalambous C, Kanakis D . Vitamin E and cancer: an update on the emerging role of γ and δ tocotrienols. Eur J Nutr. 2019; 59(3):845-857. DOI: 10.1007/s00394-019-01962-1. View

12.

Ye Y, Li J, Yuan Z . Effect of antioxidant vitamin supplementation on cardiovascular outcomes: a meta-analysis of randomized controlled trials. PLoS One. 2013; 8(2):e56803. PMC: 3577664. DOI: 10.1371/journal.pone.0056803. View

13.

Kong P, Cai Q, Geng Q, Wang J, Lan Y, Zhan Y . Vitamin intake reduce the risk of gastric cancer: meta-analysis and systematic review of randomized and observational studies. PLoS One. 2014; 9(12):e116060. PMC: 4280145. DOI: 10.1371/journal.pone.0116060. View

14.

Mohammad A, Falahi E, Barakatun-Nisak M, Nor Hanipah Z, Redzwan S, Mohamad Yusof L . Systematic review and meta-analyses of vitamin E (alpha-tocopherol) supplementation and blood lipid parameters in patients with diabetes mellitus. Diabetes Metab Syndr. 2021; 15(4):102158. DOI: 10.1016/j.dsx.2021.05.031. View

15.

Ramanathan N, Tan E, Loh L, Soh B, Yap W . Tocotrienol is a cardioprotective agent against ageing-associated cardiovascular disease and its associated morbidities. Nutr Metab (Lond). 2018; 15:6. PMC: 5775572. DOI: 10.1186/s12986-018-0244-4. View

16.

Chen F, Li Q, Yu Y, Yang W, Shi F, Qu Y . Association of vitamin C, vitamin D, vitamin E and risk of bladder cancer: a dose-response meta-analysis. Sci Rep. 2015; 5:9599. PMC: 5386108. DOI: 10.1038/srep09599. View

17.

Stratton J, Godwin M . The effect of supplemental vitamins and minerals on the development of prostate cancer: a systematic review and meta-analysis. Fam Pract. 2011; 28(3):243-52. DOI: 10.1093/fampra/cmq115. View

18.

Rutjes A, Denton D, Di Nisio M, Chong L, Abraham R, Al-Assaf A . Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life. Cochrane Database Syst Rev. 2018; 12:CD011906. PMC: 6353240. DOI: 10.1002/14651858.CD011906.pub2. View

19.

Reboul E . Vitamin E Bioavailability: Mechanisms of Intestinal Absorption in the Spotlight. Antioxidants (Basel). 2017; 6(4). PMC: 5745505. DOI: 10.3390/antiox6040095. View

20.

Saunders C, Rehbinder E, Carlsen K, Gudbrandsgard M, Carlsen K, Haugen G . Food and nutrient intake and adherence to dietary recommendations during pregnancy: a Nordic mother-child population-based cohort. Food Nutr Res. 2020; 63. PMC: 6939665. DOI: 10.29219/fnr.v63.3676. View