Atypical Hemolytic Uremic Syndrome in a Child: A Rare Case Report

Overview

Journal Clin Case Rep

Date 2024 Jan 1

PMID 38161638

Authors

Bishal Kunwor

Bishal Sharma

Suchit Thapa Chhetri

Prerana Joshi

Dipendra Pradhan

Affiliations

Soon will be listed here.

Abstract

Atypical hemolytic uremic syndrome, a rare thrombotic microangiopathy, necessitates early diagnosis and comprehensive care due to its potential severity, emphasizing the importance of a multidisciplinary approach to improve outcomes.

Citing Articles

Atypical hemolytic uremic syndrome in a child: A rare case report.

Kunwor B, Sharma B, Chhetri S, Joshi P, Pradhan D Clin Case Rep. 2024; 12(1):e8356.

PMID: 38161638 PMC: 10753129. DOI: 10.1002/ccr3.8356.

References

Zimmerhackl L, Besbas N, Jungraithmayr T, van de Kar N, Karch H, Karpman D . Epidemiology, clinical presentation, and pathophysiology of atypical and recurrent hemolytic uremic syndrome. Semin Thromb Hemost. 2006; 32(2):113-20. DOI: 10.1055/s-2006-939767. View

Goodship T, Cook H, Fakhouri F, Fervenza F, Fremeaux-Bacchi V, Kavanagh D . Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a "Kidney Disease: Improving Global Outcomes" (KDIGO) Controversies Conference. Kidney Int. 2016; 91(3):539-551. DOI: 10.1016/j.kint.2016.10.005. View

Loirat C, Fremeaux-Bacchi V . Atypical hemolytic uremic syndrome. Orphanet J Rare Dis. 2011; 6:60. PMC: 3198674. DOI: 10.1186/1750-1172-6-60. View

Raina R, Krishnappa V, Blaha T, Kann T, Hein W, Burke L . Atypical Hemolytic-Uremic Syndrome: An Update on Pathophysiology, Diagnosis, and Treatment. Ther Apher Dial. 2018; 23(1):4-21. DOI: 10.1111/1744-9987.12763. View

Kaplan B, Meyers K, Schulman S . The pathogenesis and treatment of hemolytic uremic syndrome. J Am Soc Nephrol. 1998; 9(6):1126-33. DOI: 10.1681/ASN.V961126. View

Noris M, Caprioli J, Bresin E, Mossali C, Pianetti G, Gamba S . Relative role of genetic complement abnormalities in sporadic and familial aHUS and their impact on clinical phenotype. Clin J Am Soc Nephrol. 2010; 5(10):1844-59. PMC: 2974386. DOI: 10.2215/CJN.02210310. View

George J, Nester C . Syndromes of thrombotic microangiopathy. N Engl J Med. 2014; 371(7):654-66. DOI: 10.1056/NEJMra1312353. View

Kunwor B, Sharma B, Chhetri S, Joshi P, Pradhan D . Atypical hemolytic uremic syndrome in a child: A rare case report. Clin Case Rep. 2024; 12(1):e8356. PMC: 10753129. DOI: 10.1002/ccr3.8356. View

Remuzzi G, Ruggenenti P . The hemolytic uremic syndrome. Kidney Int. 1995; 48(1):2-19. DOI: 10.1038/ki.1995.261. View

10.

Moake J . Thrombotic microangiopathies. N Engl J Med. 2002; 347(8):589-600. DOI: 10.1056/NEJMra020528. View

11.

Mele C, Remuzzi G, Noris M . Hemolytic uremic syndrome. Semin Immunopathol. 2014; 36(4):399-420. DOI: 10.1007/s00281-014-0416-x. View

12.

Noris M, Remuzzi G . Atypical hemolytic-uremic syndrome. N Engl J Med. 2009; 361(17):1676-87. DOI: 10.1056/NEJMra0902814. View

13.

Sawai T, Nangaku M, Ashida A, Fujimaru R, Hataya H, Hidaka Y . Diagnostic criteria for atypical hemolytic uremic syndrome proposed by the Joint Committee of the Japanese Society of Nephrology and the Japan Pediatric Society. Pediatr Int. 2014; 56(1):1-5. DOI: 10.1111/ped.12274. View

14.

Legendre C, Licht C, Muus P, Greenbaum L, Babu S, Bedrosian C . Terminal complement inhibitor eculizumab in atypical hemolytic-uremic syndrome. N Engl J Med. 2013; 368(23):2169-81. DOI: 10.1056/NEJMoa1208981. View