Similarities and Differences Between Three-Dimensional Speckle-Tracking Echocardiography-Derived Left and Right Atrial Volumes and Volume-Based Functional Properties in the Same Healthy Adults-A Detailed Analysis from the MAGYAR-Healthy Study

Overview

Journal Medicina (Kaunas)

Publisher MDPI

Specialty General Medicine

Date 2023 Dec 23

PMID 38138154

Authors

Attila Nemes

Arpad Kormanyos

Nora Ambrus

Csaba Lengyel

Affiliations

Soon will be listed here.

Abstract

: It would be important to know what happens to the volume and volume-based functional properties of one atrium if the size of the other atrium is larger or smaller than the average. Therefore, the present study aimed to perform three-dimensional speckle-tracking echocardiography (3DSTE)-derived quantification of left atrial (LA) and right atrial (RA) volumes and volume-based functional properties to examine these associations in healthy adults with mean and lower or higher than mean atrial volumes. : The present study consisted of 179 healthy volunteers with a mean age of 32.3 ± 12.3 years (92 males). Three-dimensional speckle-tracking echocardiography-derived LA and RA volumes and volume-based functional properties were determined in all cases. : When different LA or RA volume groups were evaluated, both LA and RA showed the same pattern of volume changes in all phases of atrial function with higher LA or RA volumes. In case of low and mean LA volumes, RA volumes were higher compared to their LA counterpart. In case of mean and high RA volumes, RA volumes proved to be higher as well. In case of mean LA or RA volumes, differences between LA and RA stroke volumes (SVs) could not be detected, but all atrial emptying fractions (EFs) were lower for RA than for LA. Some differences were detected in counterpart LA/RA total, passive, and active atrial SVs and EFs values in the presence of lower/higher than mean LA/RA volume. : In case of mean LA or RA volumes, RA volumes are higher compared to their LA counterpart, LA-SVs and RA-SVs are similar, but atrial EFs are lower for RA than for LA. If lower/higher than mean LA or RA volumes are present, some differences in patterns of changes in counterpart atrial volumes-SVs and EFs-could be detected.

References

Ammar K, E Paterick T, Khandheria B, Jan M, Kramer C, Umland M . Myocardial mechanics: understanding and applying three-dimensional speckle tracking echocardiography in clinical practice. Echocardiography. 2012; 29(7):861-72. DOI: 10.1111/j.1540-8175.2012.01712.x. View

Moustafa S, Zuhairy H, Youssef M, Alvarez N, Connelly M, Prieur T . Right and Left Atrial Dissimilarities in Normal Subjects Explored by Speckle Tracking Echocardiography. Echocardiography. 2015; 32(9):1392-9. DOI: 10.1111/echo.12880. View

Nemes A, Domsik P, Kalapos A, Forster T . Is three-dimensional speckle-tracking echocardiography able to identify different patterns of left atrial dysfunction in selected disorders?: Short summary of the MAGYAR-Path Study. Int J Cardiol. 2016; 220:535-7. DOI: 10.1016/j.ijcard.2016.06.122. View

Butova X, Myachina T, Simonova R, Kochurova A, Mukhlynina E, Kopylova G . The inter-chamber differences in the contractile function between left and right atrial cardiomyocytes in atrial fibrillation in rats. Front Cardiovasc Med. 2023; 10:1203093. PMC: 10440706. DOI: 10.3389/fcvm.2023.1203093. View

DAscenzi F, Pelliccia A, Natali B, Zaca V, Cameli M, Alvino F . Morphological and functional adaptation of left and right atria induced by training in highly trained female athletes. Circ Cardiovasc Imaging. 2014; 7(2):222-9. DOI: 10.1161/CIRCIMAGING.113.001345. View

Dini F, Pugliese N, Ameri P, Attanasio U, Badagliacca R, Correale M . Right ventricular failure in left heart disease: from pathophysiology to clinical manifestations and prognosis. Heart Fail Rev. 2022; 28(4):757-766. PMC: 9596338. DOI: 10.1007/s10741-022-10282-2. View

Hoit B . Left atrial size and function: role in prognosis. J Am Coll Cardiol. 2013; 63(6):493-505. DOI: 10.1016/j.jacc.2013.10.055. View

Jacob R, Dierberger B, Kissling G . Functional significance of the Frank-Starling mechanism under physiological and pathophysiological conditions. Eur Heart J. 1992; 13 Suppl E:7-14. DOI: 10.1093/eurheartj/13.suppl_e.7. View

Gao L, Lin Y, Ji M, Wu W, Li H, Qian M . Clinical Utility of Three-Dimensional Speckle-Tracking Echocardiography in Heart Failure. J Clin Med. 2022; 11(21). PMC: 9656185. DOI: 10.3390/jcm11216307. View

10.

Muraru D, Niero A, Rodriguez-Zanella H, Cherata D, Badano L . Three-dimensional speckle-tracking echocardiography: benefits and limitations of integrating myocardial mechanics with three-dimensional imaging. Cardiovasc Diagn Ther. 2018; 8(1):101-117. PMC: 5835646. DOI: 10.21037/cdt.2017.06.01. View

11.

Nemes A, Kormanyos A, Domsik P, Kalapos A, Gyenes N, Lengyel C . Correlations between left atrial volumes and strains in healthy adults: Detailed analysis from the three-dimensional speckle-tracking echocardiographic MAGYAR-Healthy Study. J Clin Ultrasound. 2021; 49(7):650-658. DOI: 10.1002/jcu.23009. View

12.

Muller H, Reverdin S, Burri H, Shah D, Lerch R . Measurement of left and right atrial volume in patients undergoing ablation for atrial arrhythmias: comparison of a manual versus semiautomatic algorithm of real time 3D echocardiography. Echocardiography. 2013; 31(4):499-507. DOI: 10.1111/echo.12391. View

13.

Urbano-Moral J, Patel A, Maron M, Arias-Godinez J, Pandian N . Three-dimensional speckle-tracking echocardiography: methodological aspects and clinical potential. Echocardiography. 2012; 29(8):997-1010. DOI: 10.1111/j.1540-8175.2012.01773.x. View

14.

Anwar A, Geleijnse M, Soliman O, Nemes A, Ten Cate F . Left atrial Frank-Starling law assessed by real-time, three-dimensional echocardiographic left atrial volume changes. Heart. 2007; 93(11):1393-7. PMC: 2016907. DOI: 10.1136/hrt.2006.099366. View

15.

Lang R, Badano L, Mor-Avi V, Afilalo J, Armstrong A, Ernande L . Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Eur Heart J Cardiovasc Imaging. 2015; 16(3):233-70. DOI: 10.1093/ehjci/jev014. View

16.

Nemes A, Kormanyos A, Domsik P, Kalapos A, Ambrus N, Lengyel C . Normal reference values of left atrial volumes and volume-based functional properties using three-dimensional speckle-tracking echocardiography in healthy adults (Insights from the MAGYAR-Healthy Study). J Clin Ultrasound. 2020; 49(1):49-55. DOI: 10.1002/jcu.22879. View

17.

Kaimori R, Iwakawa H, Suzuki N, Aokawa M, Tashiro H, Terata K . Asymmetric remodeling between the left and right atria in patients with advanced interatrial block and atrial fibrillation. J Electrocardiol. 2023; 80:63-68. DOI: 10.1016/j.jelectrocard.2023.05.007. View

18.

Tadic M . The right atrium, a forgotten cardiac chamber: An updated review of multimodality imaging. J Clin Ultrasound. 2015; 43(6):335-45. DOI: 10.1002/jcu.22261. View

19.

Kleijn S, Aly M, Terwee C, van Rossum A, Kamp O . Comparison between direct volumetric and speckle tracking methodologies for left ventricular and left atrial chamber quantification by three-dimensional echocardiography. Am J Cardiol. 2011; 108(7):1038-44. DOI: 10.1016/j.amjcard.2011.05.042. View

20.

Nagaya M, Kawasaki M, Tanaka R, Onishi N, Sato N, Ono K . Quantitative validation of left atrial structure and function by two-dimensional and three-dimensional speckle tracking echocardiography: a comparative study with three-dimensional computed tomography. J Cardiol. 2013; 62(3):188-94. DOI: 10.1016/j.jjcc.2013.03.011. View