Quantitative Validation of Left Atrial Structure and Function by Two-dimensional and Three-dimensional Speckle Tracking Echocardiography: a Comparative Study with Three-dimensional Computed Tomography

Overview

Journal J Cardiol

Publisher Elsevier

Specialty Cardiology & Vascular Diseases

Date 2013 May 16

PMID 23672788

Citations 16

Authors

Maki Nagaya

Masanori Kawasaki

Ryuhei Tanaka

Noriyuki Onishi

Noriaki Sato

Koji Ono

Takatomo Watanabe

Shingo Minatoguchi

Hirotaka Miwa

Yoshiaki Goto

Takeshi Hirose

Masazumi Arai

Toshiyuki Noda

Sachiro Watanabe

Shinya Minatoguchi

Affiliations

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Abstract

Background: The aim of this study was to validate the accuracy of three-dimensional (3D) speckle tracking echocardiography (STE) and two-dimensional (2D)-STE for the assessment of left atrial (LA) volume and function by comparison with 3D-computed tomography (CT) performed on the same day as STE.

Methods: LA phasic volume and emptying function (EF) were measured in 28 patients with paroxysmal atrial fibrillation undergoing catheter ablation (62±11 years old) using both 3D-STE and 2D-STE during sinus rhythm. LA phasic volume and function measured by 3D-STE and 2D-STE were validated using 3D-CT as a gold standard.

Results: The intraobserver correlation coefficient and variability in maximum LA volume assessed by 3D-STE were 0.99 and 1.4±6.0%, respectively. The interobserver correlation coefficient and variability in maximum LA volume assessed by 3D-STE were 0.99 and 0.2±4.5%, respectively. There were strong correlations between LA phasic volume measured by 3D-CT and those measured by 3D-STE (r=0.98, p<0.001). There were correlations between LA phasic function measured by 3D-CT and those measured by 3D-STE (r=0.85-0.88, p<0.001). There was a better agreement between 3D-CT and 3D-STE in the assessment of LA phasic volumes and function than between 3D-CT and 2D-STE in apical 2- and 4-chamber view.

Conclusions: 3D-STE allows more accurate measurement of LA volume and function than 2D-STE and has high reproducibility.

Citing Articles

Detailed Insights into the Relationship Between Three-Dimensional Speckle-Tracking Echocardiography-Derived Systolic Left Atrial Global Strains and Left Ventricular Volumes in Healthy Adults from the MAGYAR-Healthy Study.

Nemes A, Ambrus N, Lengyel C J Clin Med. 2025; 14(4).

PMID: 40004674 PMC: 11856870. DOI: 10.3390/jcm14041143.

Complex Associations Between Systolic Left Atrial and Left Ventricular Deformations in Healthy Adults-Detailed Analysis from the Three-Dimensional Speckle-Tracking Echocardiographic MAGYAR-Healthy Study.

Nemes A, Bordacs B, Ambrus N, Lengyel C Life (Basel). 2025; 15(2).

PMID: 40003696 PMC: 11856790. DOI: 10.3390/life15020287.

Long-Term Prognostic Power of Three-Dimensional Speckle-Tracking Echocardiography-Derived Peak Left Atrial Reservoir Global Longitudinal Strain in Healthy Adults-An Analysis from the MAGYAR-Healthy Study.

Nemes A, Olajos D, Achim A, Ruzsa Z, Ambrus N, Lengyel C Life (Basel). 2025; 15(2).

PMID: 40003640 PMC: 11856474. DOI: 10.3390/life15020232.

Insights into the Associations Between Systolic Left Ventricular Rotational Mechanics and Left Atrial Peak Reservoir Strains in Healthy Adults from the MAGYAR-Healthy Study.

Nemes A, Kormanyos A, Ambrus N, Lengyel C Biomedicines. 2024; 12(11).

PMID: 39595084 PMC: 11591753. DOI: 10.3390/biomedicines12112515.

Global left ventricular strains and left atrial volumes are not associated in healthy adults - Detailed analysis from the three-dimensional speckle-tracking echocardiographic MAGYAR-Healthy Study.

Nemes A, Kormanyos A, Ambrus N, Lengyel C Int J Cardiol Heart Vasc. 2024; 52:101411.

PMID: 38779327 PMC: 11109869. DOI: 10.1016/j.ijcha.2024.101411.