From Child to Old Man: A Slowly Evolving Case of Chromoblastomycosis Caused by

Overview

Journal Antibiotics (Basel)

Specialty Pharmacology

Date 2023 Dec 23

PMID 38136747

Authors

Carmen Rodriguez-Cerdeira

Rigoberto Hernandez-Castro

Roberto Arenas

Cecilia Sandoval-Tress

Fidencio Gutierrez-Murillo

Luary Carolina Martinez-Chavarria

Juan Xicohtencatl-Cortes

Monika Fida

Erick Martinez-Herrera

Affiliations

Soon will be listed here.

Abstract

Chromoblastomycosis is a chronic granulomatous mycosis of the skin and subcutaneous tissue caused by traumatic inoculation with dematiaceous fungi. This disease primarily affects agricultural workers, who are mostly men. We present a case of chromoblastomycosis in a 63-year-old male farmer patient with dermatosis over 50 years of evolution, with warty, erythematous, and scaly plaques that predominate on the left hemithorax. Direct examination with potassium hydroxide (KOH) revealed numerous fumagoid cells. Amplification and sequencing of the internal transcribed spacer (ITS) and translation elongation factor 1-alpha gene revealed that chromoblastomycosis was caused by . The chromoblastomycosis was treated with itraconazole and fluconazole without any improvement, and amphotericin B was administered with partial improvement.

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