» Articles » PMID: 38102491

MRI of Cerebral Oedema in Ischaemic Stroke and Its Current Use in Routine Clinical Practice

Overview
Journal Neuroradiology
Specialties Neurology
Radiology
Date 2023 Dec 15
PMID 38102491
Authors
Affiliations
Soon will be listed here.
Abstract

Currently, with the knowledge of the role of collateral circulation in the development of cerebral ischaemia, traditional therapeutic windows are being prolonged, with time not being the only criterion. Instead, a more personalised approach is applied to select additional patients who might benefit from active treatment. This review briefly describes the current knowledge of the pathophysiology of the development of early ischaemic changes, the capabilities of MRI to depict such changes, and the basics of the routinely used imaging techniques broadly available for the assessment of individual phases of cerebral ischaemia, and summarises the possible clinical use of routine MR imaging, including patient selection for active treatment and assessment of the outcome on the basis of imaging.

References
1.
Ho M, Rojas R, Eisenberg R . Cerebral edema. AJR Am J Roentgenol. 2012; 199(3):W258-73. DOI: 10.2214/AJR.11.8081. View

2.
Pierpaoli C, Alger J, Righini A, Mattiello J, Dickerson R, Des Pres D . High temporal resolution diffusion MRI of global cerebral ischemia and reperfusion. J Cereb Blood Flow Metab. 1996; 16(5):892-905. DOI: 10.1097/00004647-199609000-00013. View

3.
Han W, Song Y, Rocha M, Shi Y . Ischemic brain edema: Emerging cellular mechanisms and therapeutic approaches. Neurobiol Dis. 2023; 178:106029. DOI: 10.1016/j.nbd.2023.106029. View

4.
Stokum J, Gerzanich V, Simard J . Molecular pathophysiology of cerebral edema. J Cereb Blood Flow Metab. 2015; 36(3):513-38. PMC: 4776312. DOI: 10.1177/0271678X15617172. View

5.
KLATZO I . Presidental address. Neuropathological aspects of brain edema. J Neuropathol Exp Neurol. 1967; 26(1):1-14. DOI: 10.1097/00005072-196701000-00001. View