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Fruit Vinegar As a Promising Source of Natural Anti-inflammatory Agents: an Up-to-date Review

Overview
Journal Daru
Specialty Pharmacology
Date 2023 Dec 1
PMID 38040916
Authors
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Abstract

Objectives: Fruit vinegar is one of the most famous fruit byproducts worldwide with several unique properties. There are two types of fruit vinegar, artisanal and industrial, for consumers to choose from. This review aims to assess for the first time the phytochemistry of fruit vinegar and its anti-inflammatory effects.

Method: The present work was conducted based on a literature search that selected the relevant papers from indexed databases such as Scopus, Science Direct, MDPI, PubMed, Hindawi, and Web of Science. We used numerous terms to assure a good search in different databases, including fruit vinegar, phytochemistry, bioavailability and bioaccessibility, and anti-inflammatory effect. All articles were selected based on their relevance, quality, and problematic treatment.

Results: Literature data have shown that vinegar has a long medicinal history and has been widely used by different civilizations, due to its richness in bioactive molecules, vinegar plays an important role in the prevention and treatment of various inflammatory diseases, including atopic dermatitis, mastitis, asthma, arthritis, acute pancreatitis, and colitis. Fruit vinegar consumption benefit is highly dependent on its chemical composition, especially organic acids and antioxidants, which can act as nutraceuticals.

Conclusion: Fruit vinegar has a rich chemical composition, including organic acids that can be transformed in the digestive system into compounds that play an important role in health-promoting features such as anti-inflammatory effects throughout the control of intestinal microbiota and pro-inflammatory cytokine production.

Citing Articles

Pro-Health Potential of Fruit Vinegars and Oxymels in Various Experimental Models.

Olas B Int J Mol Sci. 2025; 26(1.

PMID: 39795866 PMC: 11720349. DOI: 10.3390/ijms26010007.

References
1.
Xia T, Zhang Z, Zhao Y, Kang C, Zhang X, Tian Y . The anti-diabetic activity of polyphenols-rich vinegar extract in mice via regulating gut microbiota and liver inflammation. Food Chem. 2022; 393:133443. DOI: 10.1016/j.foodchem.2022.133443. View

2.
Erdal B, Yikmis S, Tokatli Demirok N, Bozgeyik E, Levent O . Effects of Non-Thermal Treatment on Gilaburu Vinegar ( L.): Polyphenols, Amino Acid, Antimicrobial, and Anticancer Properties. Biology (Basel). 2022; 11(6). PMC: 9220034. DOI: 10.3390/biology11060926. View

3.
Ousaaid D, Mechchate H, Laaroussi H, Hano C, Bakour M, El Ghouizi A . Fruits Vinegar: Quality Characteristics, Phytochemistry, and Functionality. Molecules. 2022; 27(1). PMC: 8746612. DOI: 10.3390/molecules27010222. View

4.
Mumtaz S, Ali S, Tahir H, Kazmi S, Shakir H, Mughal T . Aging and its treatment with vitamin C: a comprehensive mechanistic review. Mol Biol Rep. 2021; 48(12):8141-8153. DOI: 10.1007/s11033-021-06781-4. View

5.
Maya-Cano D, Arango-Varela S, Santa-Gonzalez G . Phenolic compounds of blueberries ( as a protective strategy against skin cell damage induced by ROS: A review of antioxidant potential and antiproliferative capacity. Heliyon. 2021; 7(2):e06297. PMC: 7903303. DOI: 10.1016/j.heliyon.2021.e06297. View