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Massive Underrepresentation of Arabs in Genomic Studies of Common Disease

Overview
Journal Genome Med
Publisher Biomed Central
Specialty Genetics
Date 2023 Nov 23
PMID 37993966
Authors
Romit Bhattacharya
Ningning Chen
Injeong Shim
Hiroyuki Kuwahara
Xin Gao
Fowzan S Alkuraya
Akl C Fahed
Affiliations
Soon will be listed here.
Abstract

Arabs represent 5% of the world population and have a high prevalence of common disease, yet remain greatly underrepresented in genome-wide association studies, where only 1 in 600 individuals are Arab. We highlight the persistent and unaddressed underrepresentation of Arabs in genomic databases and discuss its impact on public health genomics and missed opportunities for biological discovery.

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