The Changing Landscape of Respiratory Syncytial Virus Infections

Overview

Journal Pathogens

Date 2023 Oct 27

PMID 37887712

Authors

Reinout A Bem

Job B M van Woensel

Affiliations

Soon will be listed here.

Abstract

Respiratory syncytial virus (RSV), a negative-sense, enveloped RNA virus of the family , subfamily , and genus , is the single most important respiratory pathogen affecting infants and young children [...].

References

Bardsley M, Morbey R, Hughes H, Beck C, Watson C, Zhao H . Epidemiology of respiratory syncytial virus in children younger than 5 years in England during the COVID-19 pandemic, measured by laboratory, clinical, and syndromic surveillance: a retrospective observational study. Lancet Infect Dis. 2022; 23(1):56-66. PMC: 9762748. DOI: 10.1016/S1473-3099(22)00525-4. View

Lilien T, Gunjak M, Myti D, Casado F, van Woensel J, Morty R . Long-Term Pulmonary Dysfunction by Hyperoxia Exposure during Severe Viral Lower Respiratory Tract Infection in Mice. Pathogens. 2022; 11(11). PMC: 9696792. DOI: 10.3390/pathogens11111334. View

Brunwasser S, Snyder B, Driscoll A, Fell D, Savitz D, Feikin D . Assessing the strength of evidence for a causal effect of respiratory syncytial virus lower respiratory tract infections on subsequent wheezing illness: a systematic review and meta-analysis. Lancet Respir Med. 2020; 8(8):795-806. PMC: 7464591. DOI: 10.1016/S2213-2600(20)30109-0. View

Coussement J, Zuber B, Garrigues E, Gros A, Vandueren C, Epaillard N . Characteristics and Outcomes of Patients in the ICU With Respiratory Syncytial Virus Compared With Those With Influenza Infection: A Multicenter Matched Cohort Study. Chest. 2022; 161(6):1475-1484. DOI: 10.1016/j.chest.2021.12.670. View

Tesari Crnkovic H, Bendelja K, Drkulec V, Juraski R, Turkalj M . Respiratory Syncytial Virus-Specific Antibodies and Atopic Diseases in Children: A 10-Year Follow-Up. Pathogens. 2023; 12(4). PMC: 10142345. DOI: 10.3390/pathogens12040546. View

Falsey A, Hennessey P, Formica M, Cox C, Walsh E . Respiratory syncytial virus infection in elderly and high-risk adults. N Engl J Med. 2005; 352(17):1749-59. DOI: 10.1056/NEJMoa043951. View

Blanken M, Rovers M, Molenaar J, Winkler-Seinstra P, Meijer A, Kimpen J . Respiratory syncytial virus and recurrent wheeze in healthy preterm infants. N Engl J Med. 2013; 368(19):1791-9. DOI: 10.1056/NEJMoa1211917. View

Gatt D, Martin I, AlFouzan R, Moraes T . Prevention and Treatment Strategies for Respiratory Syncytial Virus (RSV). Pathogens. 2023; 12(2). PMC: 9961958. DOI: 10.3390/pathogens12020154. View

Busack B, Shorr A . Going Viral-RSV as the Neglected Adult Respiratory Virus. Pathogens. 2022; 11(11). PMC: 9692430. DOI: 10.3390/pathogens11111324. View

10.

Sims D, Downham M, Gardner P, Webb J, Weightman D . Study of 8-year-old children with a history of respiratory syncytial virus bronchiolitis in infancy. Br Med J. 1978; 1(6104):11-14. PMC: 1602461. DOI: 10.1136/bmj.1.6104.11. View

11.

Willer R, Coon E, Harrison W, Ralston S . Trends in Hospital Costs and Levels of Services Provided for Children With Bronchiolitis Treated in Children's Hospitals. JAMA Netw Open. 2021; 4(10):e2129920. PMC: 8548950. DOI: 10.1001/jamanetworkopen.2021.29920. View

12.

Magro M, Mas V, Chappell K, Vazquez M, Cano O, Luque D . Neutralizing antibodies against the preactive form of respiratory syncytial virus fusion protein offer unique possibilities for clinical intervention. Proc Natl Acad Sci U S A. 2012; 109(8):3089-94. PMC: 3286924. DOI: 10.1073/pnas.1115941109. View

13.

Janse M, Soekhradj S, de Jong R, van de Burgwal L . Identifying Cross-Utilization of RSV Vaccine Inventions across the Human and Veterinary Field. Pathogens. 2023; 12(1). PMC: 9865526. DOI: 10.3390/pathogens12010046. View

14.

Li Y, Wang X, Blau D, Caballero M, Feikin D, Gill C . Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis. Lancet. 2022; 399(10340):2047-2064. PMC: 7613574. DOI: 10.1016/S0140-6736(22)00478-0. View

15.

De Rose D, Caoci S, Auriti C, Maddaloni C, Capolupo I, Salvatori G . Lessons from SARS-CoV-2 Pandemics: How Restrictive Measures Impacted the Trend of Respiratory Infections in Neonates and Infants up to Three Months of Age. Pathogens. 2022; 11(10). PMC: 9611509. DOI: 10.3390/pathogens11101086. View

16.

Langedijk A, Bont L . Respiratory syncytial virus infection and novel interventions. Nat Rev Microbiol. 2023; 21(11):734-749. DOI: 10.1038/s41579-023-00919-w. View

17.

Bem R, Bont L, van Woensel J . Life-threatening bronchiolitis in children: eight decades of critical care. Lancet Respir Med. 2020; 8(2):142-144. DOI: 10.1016/S2213-2600(19)30445-X. View

18.

McLellan J, Chen M, Leung S, Graepel K, Du X, Yang Y . Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody. Science. 2013; 340(6136):1113-7. PMC: 4459498. DOI: 10.1126/science.1234914. View

19.

HUBBLE D, Osborn G . Acute Bronchiolitis in Children. Br Med J. 2010; 1(4177):107-126.1. PMC: 2160519. DOI: 10.1136/bmj.1.4177.107. View

20.

Slain K, Malay S, Shein S . Hospital Charges Associated With Critical Bronchiolitis From 2009 to 2019. Pediatr Crit Care Med. 2022; 23(3):171-180. DOI: 10.1097/PCC.0000000000002878. View