Fatigue, Depression and Health-Related Quality of Life in Patients with Post-Myocardial Infarction During the COVID-19 Pandemic: Results from the Augsburg Myocardial Infarction Registry

Overview

Journal J Clin Med

Specialty General Medicine

Date 2023 Oct 14

PMID 37834993

Authors

Christa Meisinger

Inge Kirchberger

Philip Raake

Jakob Linseisen

Timo Schmitz

Affiliations

Soon will be listed here.

Abstract

Methods: The analysis was based on population-based Myocardial Infarction Registry Augsburg data. All survivors of AMI between 1 June 2020 and 15 September 2021 were included ( 882) and received a postal questionnaire containing questions about fatigue (Fatigue Assessment Scale), depression (Patient Health Questionnaire), and HRQoL (MacNew Heart Disease HRQoL questionnaire) on 17 November 2021. The questionnaire was returned by 592 patients (67.1%), and 574 participants could be included in the analysis. Multivariable linear regression models were performed to investigate the associations between fatigue and depression (both exposures) and HRQoL (outcome).

Results: Altogether, 273 (47.6%) participants met the criteria for the presence of fatigue, about 16% showed signs of moderate to severe depression. Both fatigue and depression were significantly associated with a decreased HRQoL (total score and emotional, social, and physical subscales; all -values < 0.0001). In particular, a combined occurrence of fatigue and depression was associated with a significantly reduced HRQoL.

Conclusions: It seems necessary to screen post-MI patients for the presence of fatigue and depression in clinical practice on a routine basis to provide them with adequate support and treatment and thus also to improve their HRQoL.

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