» Articles » PMID: 37831210

CDKN2A/B Mutations and Allele-specific Alterations Stratify Survival Outcomes in IDH-mutant Astrocytomas

Citing Articles

Homozygous CDKN2A/B deletions in low- and high-grade glioma: a meta-analysis of individual patient data and predictive values of p16 immunohistochemistry testing.

Noack D, Wach J, Barrantes-Freer A, Nicolay N, Guresir E, Seidel C Acta Neuropathol Commun. 2024; 12(1):180.

PMID: 39593128 PMC: 11590270. DOI: 10.1186/s40478-024-01889-7.


The prognostic impact of CDKN2A/B hemizygous deletions in IDH-mutant glioma.

Ippen F, Hielscher T, Friedel D, Gobel K, Reuss D, Herold-Mende C Neuro Oncol. 2024; 27(3):743-754.

PMID: 39530475 PMC: 11889711. DOI: 10.1093/neuonc/noae238.


Consensus recommendations for an integrated diagnostic approach to peripheral nerve sheath tumors arising in the setting of Neurofibromatosis Type 1.

Lucas C, Gross A, Romo C, Dehner C, Lazar A, Miettinen M Neuro Oncol. 2024; 27(3):616-624.

PMID: 39500722 PMC: 11889724. DOI: 10.1093/neuonc/noae235.


A multi-center, clinical analysis of IDH-mutant gliomas, WHO Grade 4: implications for prognosis and clinical trial design.

Wetzel E, Nohman A, Hsieh A, Reuss D, Unterberg A, Eyupoglu I J Neurooncol. 2024; 171(2):373-381.

PMID: 39432026 PMC: 11695381. DOI: 10.1007/s11060-024-04852-7.


Molecular Profile as an Outcome Predictor in Glioblastoma along with MRI Features and Surgical Resection: A Scoping Review.

Papacocea S, Vrinceanu D, Dumitru M, Manole F, Serboiu C, Papacocea M Int J Mol Sci. 2024; 25(17).

PMID: 39273661 PMC: 11395592. DOI: 10.3390/ijms25179714.


References
1.
Shen R, Seshan V . FACETS: allele-specific copy number and clonal heterogeneity analysis tool for high-throughput DNA sequencing. Nucleic Acids Res. 2016; 44(16):e131. PMC: 5027494. DOI: 10.1093/nar/gkw520. View

2.
Chakravarty D, Gao J, Phillips S, Kundra R, Zhang H, Wang J . OncoKB: A Precision Oncology Knowledge Base. JCO Precis Oncol. 2017; 2017. PMC: 5586540. DOI: 10.1200/PO.17.00011. View

3.
Perry A, Anderl K, Borell T, Kimmel D, Wang C, OFallon J . Detection of p16, RB, CDK4, and p53 gene deletion and amplification by fluorescence in situ hybridization in 96 gliomas. Am J Clin Pathol. 1999; 112(6):801-9. DOI: 10.1093/ajcp/112.6.801. View

4.
Zehir A, Benayed R, Shah R, Syed A, Middha S, Kim H . Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients. Nat Med. 2017; 23(6):703-713. PMC: 5461196. DOI: 10.1038/nm.4333. View

5.
Kocakavuk E, Johnson K, Sabedot T, Reinhardt H, Noushmehr H, Verhaak R . Hemizygous CDKN2A deletion confers worse survival outcomes in IDHmut-noncodel gliomas. Neuro Oncol. 2023; 25(9):1721-1723. PMC: 10479907. DOI: 10.1093/neuonc/noad095. View