[Cross-sectional Study of Iron Level During Pregnancy at the Mohamed V Military Training Hospital, Rabat]

Overview

Journal Pan Afr Med J

Date 2023 Oct 4

PMID 37790157

Authors

Raoul Karfo

Servilien Mpawenimana

Elie Kabre

Jean Sakande

Saida Tellal

Affiliations

Soon will be listed here.

Abstract

Iron deficiency is the most widespread nutritional disorder. Anaemia during pregnancy is common in developing countries. The purpose of this study was to check iron levels during pregnancy by evaluating laboratory indicators of iron deficiency. Our study was conducted in the Department of Obstetrics and Gynaecology of the Mohamed V Military Training Hospital (MVMTH) and included 66 patients monitored during three trimesters of pregnancy. Biochemical tests including ferritin, serum iron, CRP and blood counts were performed. The average age of patients was 28.3 years, with a standard deviation of 5.2. The prevalence of iron deficiency was 15.2% (n = 10), 25.8% (n = 17) and 42.2% (n = 28) in the first, second and third trimester, respectively. Anemia progressed from 10% (n = 7), 24% (n = 16) to 42% (n = 28). ANOVA test was used to compare the means for the parameters serum ferritin and iron, hemoglobin and hematocrit within the three trimesters. This showed a significant difference with p = 0.001. This study highlights a high prevalence of iron deficiency during pregnancy, especially in the third trimester, that would justify a systematic iron supplementation.

References

El Guindi W, Pronost J, Carles G, Largeaud M, El Gareh N, Montoya Y . [Severe maternal anemia and pregnancy outcome]. J Gynecol Obstet Biol Reprod (Paris). 2004; 33(6 Pt 1):506-9. DOI: 10.1016/s0368-2315(04)96563-5. View

Paesano R, Torcia F, Berlutti F, Pacifici E, Ebano V, Moscarini M . Oral administration of lactoferrin increases hemoglobin and total serum iron in pregnant women. Biochem Cell Biol. 2006; 84(3):377-80. DOI: 10.1139/o06-040. View

Osendarp S, Van Raaij J, Arifeen S, Wahed M, Baqui A, FUCHS G . A randomized, placebo-controlled trial of the effect of zinc supplementation during pregnancy on pregnancy outcome in Bangladeshi urban poor. Am J Clin Nutr. 2000; 71(1):114-9. DOI: 10.1093/ajcn/71.1.114. View

Malinowski A, Murji A . . CMAJ. 2021; 193(39):E1545-E1546. PMC: 8568089. DOI: 10.1503/cmaj.210007-f. View

Marti-Carvajal A, Pena-Marti G, Comunian G, Munoz S . Prevalence of anemia during pregnancy: results of Valencia (Venezuela) anemia during pregnancy study. Arch Latinoam Nutr. 2002; 52(1):5-11. View

Ruivard M . [Genetic iron overloads and hepatic insulin-resistance iron overload syndrome: an update]. Rev Med Interne. 2008; 30(1):35-42. DOI: 10.1016/j.revmed.2008.05.004. View

Espanel C, Kafando E, Herault B, Petit A, Herault O, BINET C . [Iron deficiency anaemia: clinical presentation, biological diagnosis and management]. Transfus Clin Biol. 2007; 14(1):21-4. DOI: 10.1016/j.tracli.2007.04.005. View

Nahon S, Bouhnik Y . [Investigation of iron deficiency]. Gastroenterol Clin Biol. 2000; 24(5 Pt 2):B62-7. View

Rayman M, Barlis J, Evans R, Redman C, King L . Abnormal iron parameters in the pregnancy syndrome preeclampsia. Am J Obstet Gynecol. 2002; 187(2):412-8. DOI: 10.1067/mob.2002.123895. View

10.

Beaumont C . [New developments in iron homeostasis]. Rev Med Interne. 2009; 30 Suppl 4:S307-10. DOI: 10.1016/j.revmed.2009.09.020. View

11.

Monarrez-Espino J, Martinez H, GREINER T . Iron deficiency anemia in Tarahumara women of reproductive-age in northern Mexico. Salud Publica Mex. 2002; 43(5):392-401. DOI: 10.1590/s0036-36342001000500002. View

12.

OBrien K, Zavaleta N, Abrams S, Caulfield L . Maternal iron status influences iron transfer to the fetus during the third trimester of pregnancy. Am J Clin Nutr. 2003; 77(4):924-30. DOI: 10.1093/ajcn/77.4.924. View

13.

Belkaid R, Benakli M, Hammoudi-Bendib N, Ramdani-Bouguessa N, Mahi L . [Perception of doctors in different specialties of iron deficiency and iron deficiency anemia in Algeria in 2016: the SUPFER DZ survey]. Pan Afr Med J. 2019; 33:48. PMC: 6689836. DOI: 10.11604/pamj.2019.33.48.15114. View

14.

Nahounou Bleyere M, Joulia Ekaza D, Yapo Angoue P, Datte Yao J, Nguessan Banga B, Neil Cathy A . [Heterogeneity of the iron status in the woman population during the pregnancy in Côte-d'Ivoire]. Ann Biol Clin (Paris). 2007; 65(5):525-32. View