Electrochemical Late-Stage Functionalization

Overview

Journal Chem Rev

Publisher American Chemical Society

Specialty Chemistry

Date 2023 Sep 26

PMID 37751573

Authors

Yulei Wang

Suman Dana

Hao Long

Yang Xu

Yanjun Li

Nikolaos Kaplaneris

Lutz Ackermann

Affiliations

Soon will be listed here.

Abstract

Late-stage functionalization (LSF) constitutes a powerful strategy for the assembly or diversification of novel molecular entities with improved physicochemical or biological activities. LSF can thus greatly accelerate the development of medicinally relevant compounds, crop protecting agents, and functional materials. Electrochemical molecular synthesis has emerged as an environmentally friendly platform for the transformation of organic compounds. Over the past decade, electrochemical late-stage functionalization (eLSF) has gained major momentum, which is summarized herein up to February 2023.

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