Mapping the Global Research Landscape on Malnutrition for Patients with Chronic Kidney Disease: a Visualization Analysis

Overview

Journal J Health Popul Nutr

Publisher Biomed Central

Specialties Nutritional Sciences
Public Health

Date 2023 Sep 23

PMID 37742012

Authors

Muna H Shakhshir

Divya Vanoh

Mohanad Hassan

Saed H Zyoud

Affiliations

Soon will be listed here.

Abstract

Background: Chronic kidney disease (CKD) is seen as a diverse disease and a primary contributor to global mortality. Malnutrition arises within chronic illness, which involves protein energy depletion and inadequate levels of essential nutrients. These factors increase the likelihood of death and the overall impact of the disease on affected individuals. Consequently, this study aims to utilize bibliometric and visual analysis to assess the current state of research, the latest advances and emerging patterns in the fields of CKD and malnutrition.

Methods: Extensive research was conducted using the Scopus database, which is the most authoritative database of research publications and citations, to focus on CKD research between 2003 and 2022, as indicated by title and author keywords. Then, within this vast collection of academic publications, a notable subset of articles was exclusively dedicated to investigating the relationship between CKD and malnutrition. Finally, we performed bibliometric analysis and visualization using VOSviewer 1.6.19 and Microsoft Excel 2013.

Results: Large global research between 2003 and 2022 resulted in 50,588 documents focused on CKD, as indicated by title and author keywords. In this extensive collection of scientific publications, a staggering portion of 823 articles is devoted exclusively to investigating the link between CKD and malnutrition. Further analysis reveals that this body of work consists of 565 articles (68.65%), 221 reviews (26.85%), and 37 miscellaneous entries (4.50%), which encompass letters and editorials. The USA was found to be the most productive country (n = 173; 21.02%), followed by Italy (n = 83; 10.09%), Sweden (n = 56; 6.80%), Brazil (n = 54; 6.56%) and China (n = 51; 6.20%). The most common terms on the map include those related to the topic of (a) malnutrition in hemodialysis patients and predicting factors; terms associated with the (b) impact of malnutrition on cardiovascular risk and complications in CKD patients; and terms related to the (c) dietary protein intake and malnutrition in CKD.

Conclusions: This study is the first of its kind to analyze CKD and malnutrition research using data from Scopus for visualization and network mapping. Recent trends indicate an increasing focus on protein-energy wasting/malnutrition in hemodialysis patients and predicting factors, dietary protein intake, and malnutrition in CKD. These topics have gained significant attention and reflect the latest scientific advances. Intervention studies are crucial to examining diet therapy's impact on patients with stages 1 to 5 CKD. We hope this study will offer researchers, dietitians and nephrologists valuable information.

Citing Articles

Novel statistically equivalent signature-based hybrid feature selection and ensemble deep learning LSTM and GRU for chronic kidney disease classification.

N Y, Shrinivasacharya P, Naik N PeerJ Comput Sci. 2024; 10:e2467.

PMID: 39678272 PMC: 11639220. DOI: 10.7717/peerj-cs.2467.

References

Apetrii M, Timofte D, Voroneanu L, Covic A . Nutrition in Chronic Kidney Disease-The Role of Proteins and Specific Diets. Nutrients. 2021; 13(3). PMC: 7999704. DOI: 10.3390/nu13030956. View

Friedman A, Miskulin D, Rosenberg I, Levey A . Demographics and trends in overweight and obesity in patients at time of kidney transplantation. Am J Kidney Dis. 2003; 41(2):480-7. DOI: 10.1053/ajkd.2003.50059. View

Kovesdy C, Anderson J, Kalantar-Zadeh K . Paradoxical association between body mass index and mortality in men with CKD not yet on dialysis. Am J Kidney Dis. 2007; 49(5):581-91. DOI: 10.1053/j.ajkd.2007.02.277. View

Shakhshir M, Alkaiyat A . Healthcare providers' knowledge, attitude, and practice on quality of nutrition care in hospitals from a developing country: a multicenter experience. J Health Popul Nutr. 2023; 42(1):15. PMC: 9990276. DOI: 10.1186/s41043-023-00355-9. View

Levey A, Becker C, Inker L . Glomerular filtration rate and albuminuria for detection and staging of acute and chronic kidney disease in adults: a systematic review. JAMA. 2015; 313(8):837-46. PMC: 4410363. DOI: 10.1001/jama.2015.0602. View

Nugent R, Fathima S, Feigl A, Chyung D . The burden of chronic kidney disease on developing nations: a 21st century challenge in global health. Nephron Clin Pract. 2011; 118(3):c269-77. DOI: 10.1159/000321382. View

George C, Mogueo A, Okpechi I, Echouffo-Tcheugui J, Kengne A . Chronic kidney disease in low-income to middle-income countries: the case for increased screening. BMJ Glob Health. 2017; 2(2):e000256. PMC: 5584488. DOI: 10.1136/bmjgh-2016-000256. View

Cupisti A, Gallieni M, Avesani C, DAlessandro C, Carrero J, Piccoli G . Medical Nutritional Therapy for Patients with Chronic Kidney Disease not on Dialysis: The Low Protein Diet as a Medication. J Clin Med. 2020; 9(11). PMC: 7697617. DOI: 10.3390/jcm9113644. View

Anker M, Hadzibegovic S, Lena A, Haverkamp W . The difference in referencing in Web of Science, Scopus, and Google Scholar. ESC Heart Fail. 2019; 6(6):1291-1312. PMC: 6989289. DOI: 10.1002/ehf2.12583. View

10.

McIntyre C, Harrison L, Eldehni M, Jefferies H, Szeto C, John S . Circulating endotoxemia: a novel factor in systemic inflammation and cardiovascular disease in chronic kidney disease. Clin J Am Soc Nephrol. 2010; 6(1):133-41. PMC: 3022234. DOI: 10.2215/CJN.04610510. View

11.

Cederholm T, Jensen G . To create a consensus on malnutrition diagnostic criteria: A report from the Global Leadership Initiative on Malnutrition (GLIM) meeting at the ESPEN Congress 2016. Clin Nutr. 2016; 36(1):7-10. DOI: 10.1016/j.clnu.2016.12.001. View

12.

Goldwasser P, Mittman N, Antignani A, Burrell D, Michel M, Collier J . Predictors of mortality in hemodialysis patients. J Am Soc Nephrol. 1993; 3(9):1613-22. DOI: 10.1681/ASN.V391613. View

13.

Cooper B, Bartlett L, Aslani A, Allen B, Ibels L, Pollock C . Validity of subjective global assessment as a nutritional marker in end-stage renal disease. Am J Kidney Dis. 2002; 40(1):126-32. DOI: 10.1053/ajkd.2002.33921. View

14.

Workeneh B, Mitch W . Review of muscle wasting associated with chronic kidney disease. Am J Clin Nutr. 2010; 91(4):1128S-1132S. DOI: 10.3945/ajcn.2010.28608B. View

15.

Kovesdy C . Epidemiology of chronic kidney disease: an update 2022. Kidney Int Suppl (2011). 2022; 12(1):7-11. PMC: 9073222. DOI: 10.1016/j.kisu.2021.11.003. View

16.

Ou X, Chen H, Qiu T, Yuan Y, Gong X . The impact of multidisciplinary team nutrition management on nutritional and toxicity status in patients with nasopharyngeal carcinoma. Asia Pac J Oncol Nurs. 2023; 10(7):100237. PMC: 10435935. DOI: 10.1016/j.apjon.2023.100237. View

17.

Zyoud S . The state of current research on COVID-19 and antibiotic use: global implications for antimicrobial resistance. J Health Popul Nutr. 2023; 42(1):42. PMC: 10180617. DOI: 10.1186/s41043-023-00386-2. View

18.

Kalantar-Zadeh K, Jafar T, Nitsch D, Neuen B, Perkovic V . Chronic kidney disease. Lancet. 2021; 398(10302):786-802. DOI: 10.1016/S0140-6736(21)00519-5. View

19.

Rhee C, Kovesdy C . Epidemiology: Spotlight on CKD deaths—increasing mortality worldwide. Nat Rev Nephrol. 2015; 11(4):199-200. PMC: 4379111. DOI: 10.1038/nrneph.2015.25. View

20.

van Eck N, Waltman L . Citation-based clustering of publications using CitNetExplorer and VOSviewer. Scientometrics. 2017; 111(2):1053-1070. PMC: 5400793. DOI: 10.1007/s11192-017-2300-7. View